Human Enhancement: the role of art and design (2008, Feb, RCA)

Human Enhancement : the role of art and design ((new tools and methods)
RCA
2008.02.12

Domesticating Enhancement
Jon Turney
Frankenstein
-    make creature big and strong, which he regrets

Darwin
-    descent with modification

Visions of future depend on visions of past
Shift from one to another

HG Wells
-    Darwinian education, taught by TH Huxkley
-    Invented the future through langage
-    1902 lecture ‘the discovery of the future’; when writing Anticipations
-    ‘we of the early 20th c and particulary that growing majority of us…men, no longer more than the present phase of a development….all exploits of….shriva….castles in the sand’

when bgin on changing, why stop? We are technological creatures

two visions of enhancement

1.    transcendence

World, the flesh and the devil

Genetics frustrating path to …-
Mechanical Man
‘he new man must appear to those…as a strange monstrious and..but only the logical outcome..although it is possible that man has far to go….before … becomes limiting factor….must happen sooner or later..then…mechanized man…advantage’

Herman Mueller
-    genetiiciss – long perspective on ‘out of the night’ – 1936 ‘in time to come…beast thought of the race….evoution still to come….working out of genetic methods…eugenic ideals…new characteristics….further t interests and happiness of .. god like beings…

no indication of finishing point

‘new organs’
-    which?

A technological project

Also represented in sci fi

Late 1920s, X-ray showing genetic mutation made its way into sci fi mags

A ra nge of possibilities

Not sure much has been added since these

Post WWII

Now a more technological project
Not speculative
Chance to make it happen
Genetic engineering – life extension –

Early 1960s, prospect of immortality visible
-    first proposal of extending life

freezing organims and thawing

achieve immortality by having frozen, then reanimate

this first strand is the grandest one

Harrington ‘the imortalist’ 1969
-    wider range o cultural and philosophical than Ettinger. Now useful text for transhumanist movement
-    starts by saying ‘death is an imposition on the human race and is no longer acceptable’

how you get there can vary

2 kinds of taken for grantedness

first, that can modify

this runs through a l

Adrian Wolfson – 2000 – ‘life without genes’
-    abstract vision of biology as a searching design space
-    all virtually present in some realm
-    biological search, but if mae more systematic can plumb more areas
-    ‘when we have chartered…natural evolutionary…fully in a position to…modify living things….life willl enter anew….no longer historical domain of natural selection…instead.construct and design new living things…’

Other books
‘ fukuyama, essentialist view ofHN;

Greg Stock
-    lets move to next stage of evltion
-    it’s in our natre to expt
-
grand narratives on human lives

Lee M. Silver
-    drawing on Huxley, etc

Singularity
-    moment occur when humanit transcended
-    2030 acording to Kurzweil
-    humans wil not be most evolved form of intelligence

commuication
-    fiction and nojn-fiction boundary highly problematic

Singularity not really a story
-just says eth after will be different
- cannot write about end of the world

need to sidestep into new reality

if singul=laiy means anything then culture should be so different that cannot say anything about it

‘your speculation is as good as mine’

other level of enhancements – lower level
-    putting fuel injection into cars, for eg

these were adopted and developed to
Vern Vinge – singulairity

-    1960s speculation on drugs, computers and cyborg

in sci fi, people take adv of a consensual future from which to write

currenty consensual feature includes these features

ME: how do you write unforeseen consequences? Do the unforeseen consequences of sci visions cohere with what actually took place?

State of art for enhancement limited – prozac and steroids

Still quite limited

One eg.

Novel 1992 – Greg Egan – sci fi author ‘Quarantine’
-    enhancement is incidental, though human modification is central
-    centres on quantum realities
-    consider argument between two of key characters, one defending brain modif, trashuman rhetoric’
-    ‘do you think that brain wiriting from natural selection…peoples attempt to change..touchstone of perfection….god hasn’t done a perfect job….take a long time …to grow out of that bullshit…outdated heap of excuses for the things we couldn’t have, but now we can’
-    also offers image of possibilitie of everyday enhancement – protagonist in flight must disguise himself, what could be more traditional than changing colour of skin: ‘many of the small traders start opening for business around dawn..nanoachines before strets become crowded….’breaking down…melanine in my skin..i stare transxied…as they fade from the dep black…to an olive complxion….reminisent of my grandfather….it’s absurd but pissing away my skin colour is at least as disorientating as….’

Domestication o enhancement is now pervasive

eg. ?Health and safety executive – upstream – foresight – might expect about conditions of workplace, but framed generously – 10 yars ahead – had 4 scenarios – in each one, they assume some technologies of enhancement will be deployed – suggested that in most auspicious scenario ‘digital rose garden’ rdescribe heightend comfort with managing risks, heightened…transhumanist 20s…..pharmacological….extrme sports enthusiasts’, less desirable, use of performance enhancing drugs imposed by company; corporate training involves training in their use; worse one involves use by organized crime – fourth option to use to cope with multiple jobs, to look after aged

was going to talk about Freeman Dyson and domestication of technology

Questions & Answers

Anders: prob with singularity, all thinking stops. Might be trends towards transitions; for singularity might; foresee big things happening and this makes us stop thinking about it

AXXX: coming from largest AL lab in world, they think in 500 years might work out how nematode worm function. Brain computer interfaces -

Mark: whose points of view do we give credence to – whose vision – eg. Delphi study; what is the science going to be?

Oron: an artist worked on Singularity. ME: Check who. I’m concerned that singularity appears apocalyptic

Anders: concerned about this idea that singularity is some sort of religious conviction. I’m now trying to defy idea of superintelligence; we can get some form of superintelligence quite easily; aspects of singularity get lost since people get caught up in apocalyptic trance

Jon: James Martin said Moore law will continue; don’t call artificial intel, but non-human intell;

James: dog project; wolf was peak of dog evolution; now changed  evolutionary characteristics; domestication has diminished; it’s ok as they no longer need them; senses redundant somehow;

Jon: standard line – genetic modification – dogs

Oron: domestication led to shrinking brain;

Jon: freeman dyson – david brind – think about conseqs of future technology is what would it be like if everyone had it – flower shows; bilt a whole culture around modifying organisms; genetics of butterly wing colour – some artist is probably doing it

Design Fictions
Tony

How fictional/unrealistic design can play a part in how we think about biotechnology

Not about predicting t future or forecasting

Designers naturally domesticate technologies
-    atterns of consmption

run through various types of design fictions

sketch book

Oron Catts – victimless meat

Wh the process of domestication might hav on

Dressing the Meat of Tomorrow
Ames King

Interested in designing the meat

What would it look like?

What will be different about this meat?
What size?

Family sies? What family?

Memnto Mori
Michael Burton

Grow hair of loved one after theyhave died

Fiction is in the behaviour
Assumes something has changed in society
Has become normal
Not saying this is a good idea, but what would people feel about this

Thr+ill
Mikail Metthey

These are al 4 week projects

Engineer illness out of our lives

Maybe illness will become a recreational activity

Place where people went to infect themselves

Reasons: hallucinating, like drug use or to connect with previous selves

Proposing an environment

Cross between a car park, sick room and a pub

Recuperation beds

Indirect way of dealing with implications of technologies, rather than becoming obsessed with t technology itself
They do become sci fi

The Race
Michael Burton

Certain concept of healh care, based on particular notion of ecysystem

Question with ay rwe relate to nature

Maybe a different notion of health will emerged

Began with maggots; today could be used to treat infection, but most people disgusted by them

How to present maggots
Biophilia Cinic
Expose ourselves to constructive germs

Modify lamb to be extra dirty and spread to us

Future Farm
-    body becomes farm
-    refer to organ farming
-    funghi grown onbody used by some company

body, activate genes and mutate to embrace more symbiotic nature
-    woman facila hair developed into a cage for grasshopper as nest

these are iconic

Chrono_shredder
Susanna Hertich
If it were possible, to hibernatre
Not to explore adv, bu how attitude towards time might change
Made clock – chronoshredder, while asseep each page of calendar shreds; conserving energy; might live longer, but life is passing

Evidence Dolls
Dunn and Raby, Pompidou Centre, 204-5

Produce design project for design as a form of critique
To raise issues
Hypothetical product called evidence doll

Prior bio projects in dept, someone would do a project about not laving genetic traces
Ways of masking

What about for woman
-    dna ‘penis drawers

samples of tissue analysed
how might impact on dating, etc

each doll was customized to represent lover
-    philosopher at oxford
-    fantasy lover
-    heartbroken woman

capture conversation

‘I would go and get the DNA stuff tested. There’s something romantic about collecting a hair sample..there is something lovely about that’

dvd of actress orating the interviews

‘Everything comes 10 years later.in the project, we are trying to move upstream

turn fiction into

design fictions could be constructive

Biojewellery
Tobbie Kerridge, Nikkis Stott, Dr Ian Thompson

New form of wedding ring,
How could bioengineering impact on commitment
Take bone from 2 lovers, worked on by jeweller to create  ring
Once it got to this stage, generate interest, wrked with engineer Ian Thommpson to engineer
Found couples who wanted to donate ring
Once project becomes real, develops more focused
Eg. how identify an audience representative of real people
Eg. peple already interested in body adornment are interested
Got to point where wanted to take sample, but could not find hospital that would take it for poetic reason
Poetic need becomes a vald need

We discovered that when have wisdom teeth removed, also bone tissue, which could be harvested

Indirectly we access labs in imperial college
Might start in fictional, then through vision end up in producing a product

Practical side not exclsive or

Questions & Answers

Jens: what does it change when becomes a reality? To do it the other way around, more hermenutical approach, what does the relative factors change?

Tony: on going debate on interaction in design; extremely difficult to get access to labs; where take more classical design approach, model more poetically, is easier.  When at this point, are making a decision about wanting it implemented. When started project, consulted bioengineers; what we’re trying to do with these projects is sit in fuzzy space – between moral ground – ; interesting space between idea of fiction, reality and fantasy that we can occuy and have different purposes

Joanna Z: science – what kind of relationship exists between these projects and ttradl discourses of science; wary of sci art collaborations – have been v conservative – artists trying to get some of scientists money – so, describe what you do with students as different; other q is whether, destination of projects, where they are going; just a conceptal exercise to become better designers? Are they aimed for galleries

Tony: where this work sits in the world is a big isse; don’t want to be seen simply as art for galleries; as a designer, if categorized as art, then can be wacky; but when proposals about alternative health care, people more wary; when someone says it’s art, leads to specific conntations; imp that we present as designl bt aren’t places in design to present it; so end p crossing over intogallery spaces; MoMa new york will display some of these works; we’re very aware of sciart and we are quite critical; we try to look at science as driving focce and ask how are we going to engage; instead of designing applications, we look at implications; one of the roles is as a provocation; these things are quite banal, quite down to earth, not to critizes but rather than let natural flow happen, by looking at positive and negative outcomes, try to stay way from that; one thing we’re really missing so far is how to make that leap; connecting to organizations to have impact is next step;

Anders:  qite a bit of my work might be on wrong questions; what enhancements do people want; a day dreaming enhancement might be better than a memory enhancement; find out what people wish for is needed

Tony: V&A project looking at visions of teenagers for enhancement; went into a school with 10yr olds; talked about nano and bioart, worked with teacher to brainstorm and came up with over 100 genetically modified toys; no shortage of imagination; processes for facilitating interactions and facilitating through plicy makers to go to higher level, not sure how would happen; lower level is easier

XXXX: what if work with ethicist

Tony: Elio Caccavale is doing this; working at PEALS; trying to speculate on what happens when technology allows for different family structures to emerge; trying to create serious design hypothetical capsules to act as medium for conversations;

SymbioticA – a model for artistic engagement with t life sciences
Oron Catts

Recently been changed to a Centre.
Miranda Grounds, Stuart Bunt and Oron Catts

Life asa raw material
-    HG Wells, 1895 – We overlook only too often the fact that a living being may also be regarded as raw material, as something plastic, something that may be shaped and altered’

Ear on back of mouse – ear fell off two weeks after those images were taken

‘fighting the hype’
-    crusader against genohype
-    Keynote address at genomics and society meeting (I will ask them to change their name)

Artistic lab

Critique of life sciences

Steve Kurtz, ORLAN,

Not just a production residency, but research, so not reqd to come up with outcome

Only masters in Biological Arts offered in a science faculty in t world

Also engage in exhibitions and symposia

Core project: Tissue Culture and Art Project (initiated in 1996)
Oron Catts and Ionat Zurr

Promoting notion of useless research

To engage with ideas, should design objects for cultural discussions

We refus funding from pressure groups

Would never accept funding from biotech companies

But our work is funded, but not by sciart funding

History of Living-Fragments / Semi-Living
-    1885 Roux embryonic chick cells stay alive in a saline solution
-    1907 Harrison’s first partial life entity; amphibian spinal cord in lymph clot
-    1913 Carrel grows cells in cultre for long periods – fed regulary under aseptic conditions
-    1948 first animal cell line (mouse)
-    1951 HeLa cell line established
-    Standard of Tissue Culture (model, tool)
-    1990s – Tissue Engineering / regenerative medicine /antibody production / non biomedical use

Eduard Uhienhuth wrote in 1916
-    ‘Through the discovery of tissue culture we have, so to speak, created a new type of body on which to grow the cell’

Carrel
-    regarded a Dr Frankenstein
-    claied his lab in Rockerfella institute was inspiration for Hollywood rankenstein

New Kind of Body – the tecno scientific body
-    semi-living entities ‘cared’ for in a techno-scientific body

problem with humancentric view

when examine bodies, notice similarities

Tissue culture as a science
-    1910-1930

semi-living dos not seem to conform to either Linnaean taxonomy nor molecular systematics

Nante

Helacyton gartleri – a new species
Van Velen and Maiorana 1991
-    ‘species originated in diverse ways. HeLa cells are t best-known cultured cells of human origin…’

McCoy cell line – human/mouse cells
-

Steven Erfelt

Cell fusion
Break of membrane

The Pig Wings Project (2000-2003)

Questions & Answers

Anders: You say uncomfortable with human enhancement but what about biomass?

Oron: yes

Jo Z: engagement aspect; how is agenda of provocateur – moralistic way of teaching -

Oron: 2 roles, artist and provocateur;

Tony: what wouldn’t you do? (ethical boundaries to performance?)
Oron: some of the work in SymbioticA I find disturbing, but I wouldn’t censor it eg. nerve cultures; engaging with animal also engaging. Became vegetarian after victimless meat project; but as long as society is utilizing animals, artists at least have a right to do the same – implicit and explicit violence; I hold 5 ethics approvals for artists to undergo biopsies on themselves for their work;

Jimmy: Kevin Warwick’s brain cell work – culturing brain cells from rats, projecting when human brain cells might be cultured;

Oron: we were involved in a project that was doing this;

Jens: becoming vegetarian – Peter Singer – victimless lover – singer wrote paper for art magazine, artist killed animals for photograph, arguing it is unacceptable,

Oron: in Singer’s recent book, doesn’t say shouldn’t eat meat, but should eat ethical meat; Craig Ventor – said about misuse of biological knowledge;

Presence/Representation – Metaphore/Metonymy: Approaches to Art involving Biotechnology
Jens Hauser
jhauser@club-internet.fr

presence –

Liverpool FACT exhibit – curating of presence effects

Iconicity

Technological visualization tools

Reading images – how far is appropriate?

Image instead of text

NYAS – Art and Biology conf, April 2007

Many scientists complain that have powerpointization of science – hollywoodization

To engage artists, stress signif points

Edgard Varese (1883-1965)
-    composer sound sculptor visionary
-    music, embodies new world

why does music produce better presence effects than visual arts?

What would an art be like that achieves productive tension?

FACT conference

Denis Noble – synthetic biology – ‘the music of life’
-    played song on his guitar for start of presentation
-    stress not to search for programme, all about harmony

title ‘sk-interfaces’ to avoid pointing to the future.

‘exploding borders, creating membranes’ – sub-title of exhibition

not a sciart show, not illustrating scientific knowledge

Hans Ulrich – meaning effects vs presence effects
-    ‘Production of Presence: What meaning cannot convey

should not dance to a tango with lyrics
-    lyrics disrupts tango
-    deprive full pleasure of fusion between tango music an movement of body
-    when dancing, even most proficient dancers cannot grasp lyrics

Victimless Leather

The Eighth Day-  Eduardo Kac
-    biobot moves with colony; biology invades mechanics
-    camera accessed by web audience

Meaning culture vs Presence culture

Quoting: artists as seismographs –

Questions & Answers

Claim that rate of viewers at FACT is five times higher than other exhibits

High emphasis on training of gallery personnel

Mark: mechanism for recording peoples reactions to exhibit

Jens: phd student from york university doing audience research

Tony: does the emotional response matter to you?

Technologies, Art & Identity
Sandra Kemp

Future Face

Photograph
-    how are artists, technologists using it?

Peter Butler – face transplant surgeon

Enhancement, identity

‘Still life with stem cells’

‘lump’ – Life form with Uninvolved(?) Mutant Properties

Human Mutant Project

Patricia Puccini
-    FRankentstein’s mistake, not a good parent

What constitutes a family

Thomas Broomfield’s ‘Misfit’

Rhona ‘Animal/Hman’

Doesn’t take sides

Social values / relationships that count

‘Give your child a chance in life, don’t leave it up to nature’

Kac’s Bunny
-    feel different if it’s your pet bunny

Penny McCarthy
-    ‘clones live in the fridge’

Orson Welles – DR Moreno ‘ existence limits of plasticity unlimited form’

Anthony Gormley – all art is about what it means to be alive

Production and consumption of visual

Much more media coverage in science than art

Media and biology have ben profoundly visual practices

Diagnosis relies on eye and ability to learn from

Richard Sennett – ‘The Craftsman’

Challenge t traditional notion of beauty

Classical aesthetic theory no longer applied

Keats ‘no longer know what beautiful is’

Portrait Gallery – Sir John Sulston – first genetic portrait called ‘A Portrait’

Stelarc

Re-enacted?
‘if alter architecture of body…alter body’s mind’

Gary Schneider
-    genetic self portrait
-    Columbia Medical School
-    XX specimen
-    Looking beneath surface of face, redefining portraiture

How no represent personhood or identity|?

Sensibility – emotion, attraction

Affect

Oscar Wilde – Life Imitates Art

Ethics and Aesthetics

Artists always loking for new material

Informed resistance vs hysteria

Foucault – task is to refuse what we are not disXXX what we are

T H body is central to explorations on these XX

Larry Miler
-    genetic code
-    copyright  certificate

ME: Bioart as Bioethics

Will t face continue to be shaped by evol or will we customize

Where does a face begin and end?
First face transplant was a replant
-    10yr old girl, hair caught in something and ripped face off

2005 face transplant
- she feels she’s lost substantial part of identity

1992 Francis Dagony – psych emerges from complex structure
interior and exterior ‘threshold’ same in portraiture

upon seeing of first phoo portrait
-    ‘shadow of the person’

Kathryn Ikan(?) – ‘Elle’
-    AI and movement sensors
-    Art, not interaction, but open, flawed system, whose viewere and art work esthetic own process of enjoyment (NOT SURE THIS IS RIGHT)

Real and Virtual

Intellectual Property – 199-2000
-    Donna McLean applied patent on herself – GB00001800
-    ‘It has taken 30 years of hard labour’

Yvonne Spielmann (2007, December 6, University of the West of Scotland)

Yvonne Spielmann seminar
6 December 2007

Japan research

Aesthetics
-    hybridity
-
Cultural studies
-    modernity, colonial, Stuart Hall
-    closing down of debate
-    Romly back to syncrhotism

Common ground between themes?

Blind spots:
Media people specify different types of convergence tend to say that analogue media reality – each photo camera, chemical, electronic – say hat none of them apply anymore, since area of simulation; they call this digitl and hybrid, since no physical reality; if combine, then hybrid

This is often neutral to outside world, but not debate of different cultural influences. Now q over global.

In CS, always vague specification of media

Lack of understanding of the media’s specificities
Including evol of genre, technology, etc

So this is a bigger blind spot, though political understanding of hybridity politics
-    nationalism, etc

eastern western compositions

how specific thought processes have been reworked

Fiona Tan
-    Indonesian artist, raised in Netherlands, photographer
-    Represn of modernity within media in 20th century
-    Also with performativity of medium
-    Transgress
-    Comment on content, but also specific apparatus of the medium
-    Creating dynamics and possibilities of change
-    Film and video used to rework other

Art Historians
-    auber XXXX
-    ar
-    human size scale installation

interested in exemplary

plurality, postmodern,

image in a dynamic

hybrid, because in between

projected film of photograph of people standing still

used to classify people and society

she brings an external

-    sarah ahmed – familiarity

western socialization of 20th century media

then, she travels to japan and does video installation in temple in souther Kyoto

‘Saint Sebastian’
-    arrow being shot.
-    Target not the focus
-    Refers to Christian mythology, but there would show tortured body
-    She takes position of san Sebastian, shooting back from camera, victim position captured by film maker, also a gender change

Indiv not s indiv, but as exemplary of particular profession

Tang

Sanjusangendo Temple in Kyoto, each year on Kyoto

Hiroshi Sugimoto – famous Japanese photographer
-    still photography, horizon lines
-    Sea of Buddha
-    Appears as same image, but they are each different – taken from 1000 buddhas
-    Impression of single image is product of modernity.
-    Require knowl of the 1000 buddhas to know that it is not simply duplication

Is this specifically Japanese approach in photography

Sugimoto – show in Rapongi

Shoichi Auk
-    Freshfruits

Katrin Paul

Tokio Hotel

Masaki Fujihata
-    Making of Landing Home
-    Gps, angle of camera.

Ethical Futures

Ethical Futures
London, RSA.

AGENDA
09.00          Registration

09.20           Audience seated in the Great Room

09.30 – 09.40      Welcome – Matthew Taylor, Chief Executive of the RSA

09.40 – 10.10       Panel Discussion – Communicating the issues:  enriching the dialogue
Our perceptions about scientific advancements are influenced by information that we receive from           a myriad of sources.  Can we trust the quality of the information in the public domain? Is there a           connection between this and our overwhelming negative response to some new and emerging               technologies?
Chair: Oliver Morton – Chief News & Features Editor, Nature
Dr Anjana Ahuja – Features writer & columnist, The Times
Cory Doctorow – Science fiction writer, journalist and blogger

10.10 – 10.20     Audience participation

10.20 – 10.30     Short story competition award presentation
RSA short story competition on our vision of the future

10.30 – 11.00     Coffee break

Presentations
An exploration of country experiences in developing ethics frameworks

11.00 – 12.20    Session chair: Dr Jonathan Carr-West – Programme Head, RSA

Japanese Bioethics and Enhancement– Prof Takao Takahashi

1.    reflective equilibrium
2.    enhancement debate in japan

history of bioethics in japan
-    from 1970s to 1980 beginning
-    1969 – Japanese Asoc of Med Law
-    1971 – principle of Informed Cnsent in Tokyo
-    1971 – Mitsubishi — Life Science Institute of Ideas

second period
1982 – first ethics committee
1983 – first IVF baby born in japan
1985 – mass media on bioethics
1988 – Japan Assoc of Bioethics

3rd period
1993- guidelines for gene therapy
1995 – first gene therapy
1997 – organ transplant aw
1999 – firs organ transplant from brain-dead person
2000 – human cloning law
2001 – guidelines for human genome research
2007 – guidelines for end of life care
agenda: surrogacy, revision to organ transplant law

Taking Life and Death Seriously – Bioethics from Japan
-    Advances in Bioethics – vol.8, Elsevier

Reflective Equilibrium
Moral judgements, moral intuition, custom
Basic concepts basic principles
Intermediate principles, law, guidelines
(via Interpretation, abduction)

no level is absolute
coherentism

subcom of human embryo research: structure of its argument

moral judgements, moral intuition, custom
-    safety donor rights, right to research, usefulness, disclosure

respect for human dignity
-    prohibition against dealing as only a method
-    prohibition against identity of human species

Current Sitn in Japan on Enhancement
-    public interest
o    not strong
o    prefer surrogate mother to designer baby
o    Ritalin – abuse, attract media
o    Cyborg – only in few tv progs
o    Doping – prob of sport
•    Make too much of safety
-    research interest
o    cannot be solved by Beauchamp and Childress’ principles or respect for dignity
•    search for not-borrowed original principles or, reinterpretation of existing principles
-    16th Annual Assoc of Biethics Conf (2004)
o    first appearance at conf
o    agena: defn of enhancement, classicifcaitons
o    discussions of funl concepts (therapy, self, dignity, autonomy goodness)
-    18th Ann Ass Conf (2006)
o    aenda: nature of life, dyanics of sci, economics
-    19th Conf (2007)
o    brain enhancement, SSRI, genetics

Characs
-    general rather than specific
-    emphasis on other countries
-    re-examine fundamental concepts rather than applic of existent principles (philosophical dialogue)
-    reflective equilibrium
-    moral intuition to criticize or deduce fundamental concepts
-    solidarity

Enhancement and Japanese compatibility
-    Reason (right way)
o    Through history, customs,
o    Prudence (Yamato Gokoro), unselfish
o    Customs, bottom-up
-    Value as endurance – customs, conventions
-    Sympathy – natural bond of humans
-    Life – soc like living thing

General view
-    ambiguity of life
o    self-preservation, improve enviro
o    inevitability of mistakes, aging dath
•    negative, but is opposite o ideal of machine
-    human dignity basd on ambiguity of life
o    respect for other
o    sympathy for vulnerable, care for others

Structure of morality based on ambiguity of life
-    moral sentences, customs

Where is permissible range?
-    if A exceeds, then B as brake
-    permissible ranges
-    therapy is most famous
-    natural

Within Japan
-    ambiguity of life
-    weak self
-    sympathy
-    uncertainties of life
-    natur’s divine power
-    child like a god
-    abandonment (virtue, ideal, leads to enlightement)

Ethics and emerging technologies in America – Prof Nigel Cameron

3 accounts of emerging technology

nanotech discussion has led
national nanotech intiative in US, by Clinton
2003 – 21st Century Nano R&D act

next fiscal year $1.4b for Institute

broader ethical implications
AI
ELSI
Language in act not tied to funding trends

Controversy among people about slowness of funding, not just for ELSI but also safety, toxicology

On Friday, I was chairing conference at Press Club in Wasington

Initiatives
-    I’ve been involved with 5 federal workshops
o    Cogntivie enhancement
o    Nano and convergence
-    No evidence that these have fed to policy machine
-    But evidence fo pre-debate

This year, re-authorization process

Tendency to play down radical implics

Nat Ac of Sci
-    produced report
-    referred to 2 of 6 concerns, dismissed as sci fi
-    but a few month before, national lab convened workshop on cognitive enhancement

discouragement of public conversation

National Science foundation
-    lead in nano
-    convened series of conferences, sep from nano and nano and soc confs
-    converging technologies
o    2003 – Roco and Bainbridge – NBIC doc
•    controversy, since occasion of European report
•    European response
•    Euro group said American approach not NBIC but of Human Nature and Machine nature
•    Europe seen as a policy doc, which was a misunderstanding
•    Object lesson in how not to do things, but also in how they were done

‘Nanoscale’ book by Cameron

Converging Technologies
-    suggests implics are World Peace
-    become one World brain
-    interpreted as policy positions of US government

3rd Narrative
-    US President’s Council on Bioethics
-    Estab for Cloning primarily
-    Beyond Therapy
o    Open ended discussion, saying enhancement is most imp q we face, bt also v difficult to come to terms with
o    Staff report, no policy recommendations or status
-    Readings doc – stories
o    Context for conversation
-    Most controversial for role in stem cell, though first formal decision was to disagree with Bush on therapeutic cloning. One reason for why policy role limited

These 3 strands on pre-debate

Observations:
-    predebate character shows difficulty in main-streaming which we are discussing today
o    public engagement strategy in Europe
•    2 possible outcomes.
•    Keep as peripheral discussion
•    Priming pump for mainstreaming, bringing about
•    Partly why developing new think tank in US, since absent
•    Cinderella character of bioethics debates
-    Converging Technologies model interesting, branded by NSF. Europ group developed alternative term. Nano are converging
o    Convergence of humanities and social sciences
-    Global dimension
o    US representatin at various sitns. Eg. human cloning vs UK
o    US also on UNESCO’s Bioethics and Human Rights

What is the European Group on Ethics in Science and New Technologies thinking about?
Prof Julian Kinderlerer

What is the EGE?
-    set up in 1990s, by President of Commission to advise

anything on sci and technology thought to be o signif in Europe

deliberately consists of fewer members than states in euro, so represents indiv, rather than a country

v difficult to put into English views of colleagues, biggest problem

Directive XXXX.:
patents on biotech and life
-    think about general, not indiv

Directive 2001/18
-    release of GMOs into enviro and marketing. We are given role in thinking about general ethical issues

recent activity
-    Opinion 20: ICT implants
o    Indicated happy with use of enhancement technology to bring human individuals within normal range, but not further. So, could replace lost or malformed foot or heart. But to enhance an athlete to take part in Olympics, falls foul of ant-doping legislation.
-    Opinion 21 (2007): ethics of nanomedicine
o    Specifically didn’t talk about enhancement
o    Only modern nano on medicine.
o    Technology offers poss of new diagnostics and preventive
o    Concerned that moral duty to make affordable health care available to all on fair and equitable basis
o    Concerned that could improve only wealthy
o    Also looked at risks
o    Economist last week on manner of risks of nano have not been assessed properly. Not technology to do risk assessment. EU recognized
o    These are policy docs. EU decided now major investment in risk and ethics of converging technologies
o    Spending more on technology than risk and ethics
o    Recognizes that understanding and preventing risk has low priority in research world.
o    With risk research, public confidence in technology could be reduced in real or perceived dangers. Sometimes perceived greater danger.
o    Cosmetics concern, since don’t require much risk analysis. But are they dangerous? How far into skin do they permeate?
•    Will return to this issue
-    Opinion 22 (2007): human embryonic stem cells, under FP7
o    US sitn permeates Europe.
o    Opinions of group, mirrored Europe
o    Germany, stem cell hardly committed. Not allowed to make or use stem cells unless country fro, which used is fully member of FP7 eg. if stem cell from Israel, can use in Germany. Italy, Ireland, Poland, cannot.
o    If brought to group, would never have had consensus
o    How bridge gap?
•    Chose to do so by political compromise
•    Worded FP7 carefully.
•    Identified variety of techniques t permit use of ESC in Europe without getting anybody XXX.
•    Eg. cant use stem cells that have been made except those in countries from FP7 – but cannot make them with money from FP7
•    Group felt strongly that cells must only be for medical research, not for other purpose eg. replace animal exptn, so only direct medical purpose, not indirect
•    System: proposal to EU, then scientific eval, then ethics eval, then reps of EU states – purely political
-    Now, due to FDA, look at cloned animals for food
o    Caused signif probs
o    Mainly cattle
o    For dairy cattle, few bulls used worldwide
o    Average bull produces enough semen for 20-100,000 calfs per year
o    Don’t need so many bulls
o    So need system for not producing monoclonal popn
o    For meet cattle, have prairies whee cattle roam and bulls roam with them
o    Difficult to improve
o    So, produce clones of bulls and improve quality of bulls.
o    Don’t need in Europe, since don’t have same extent of roaming
o    We were worried by fact that pre-implantation, have problem.
o    During pregnancy, lose greater proportion of implanted, than for AID.
o    Large number die during life
o    Animal welfare, not safety, is main concern
o    Concern about WTO legal action for unfair barriers to trade
o    Need to look at more carefully, than system in US permits
-    Next, industrialized agriculture

We believe we will be asked about enhancement technology soon

Bioethics policy and debate: a UK perspective
Hugh Whittall (Nuffield Council on Bioethics)

Previously civil servant – human tissue branch

Won’t speak on HE debate, since not much polic implics yet. Mainly academic

Gov and advisory bioethics
-    HGC
-    NRES
-    GIC
-    GTAC
-    APC

Regulatory authorities
- HFEA
- HTA

indep bodies
- Nuffield
- BMA Med Ethics Com

estab in 1991

indep body
2004 review: gov decided not to establish own bioethics committee

3 core functions
- identify and define ethical qs, respond to public concern
- make arrnagmenets for examining and reporting such questins to promote public understanding and discussion
- policy focused

quarterly meetings of council
16 members
new topics reveiwd at horizon scanning

topics
-    novel, complex, timely, allow NCOB to make an impact

working party estab to consider topic in detail

working parties

impact on public debate
-    media coveage
-    public events
-    education activities

working with Nuffield curriculum centre
provide materials for use in schools
science and citizenship curricula
plays in schools

what about adults?

We don’t have a single ethical framework that in the UK we apply to ethics in public policy

Rather, we tend to identify values relevant to particular case

What language do we use to communicate?

Need a public engagement with ethics

Enhancement ok, but need o provide underlying language with which to engage on particulars

12.20 – 12.45    Audience participation

Is there a notion of what a human being is that informs your debates?

Hugh: no. unfair to pitch to our org.

Prof Takahashi: idea of human dignity not complete. Right to self determination must be based on concept of life, not human being. What is life frames our approach.

Nigel: we operate on assumption that we know what human is, even if cannot define. At functional level, this is a non-subject. Notions of courage, etc – virtue – heart of what it means to be human. Threat is technological fix that make unnecessary.

Julian: priest and rabbi asked when life began: priest said moment of conception, rabbi said when dog dies and kids leave home. Between I and polish group on group, we are completely different. Do not wish to remove these differences. Harmonization in defining human would lose a great deal. Eg. live in south afria ecause wanted to go to non-western soc, to see what they are acing. Concept of IP presumes indiv autonomy. But not present in other cultres. Should we harmonize or understand differences?

Q: thought Hugh Whittel’s idea of having a language is fundamental. Practice of defiing values is key to international affairs, consensus and good governance. Prob of defining values is need to differentiate between amount of value ascribed by indiv to a partic quality. Science of thinking and eval that have not establishd for thinking about this prob.

Q: religious recognition outside of western?

Hugh: must measure values that come into conflict. If look at other cultures, will help.

Prof Takahashi:

Nigel: how get public discussion between different types of people.

12.45 – 13.45    Lunch

13.45 – 13.50     Book launch

Presentations
Current research is posing difficult questions about our future at both the individual and societal levels.  This session highlights some of the work and implications at the forefront of science.

13.50     15.20        Session chair: Prof Igor Aleksander – Prof of Artificial Intelligence
Humanoid Robotics, Culture and Society of Japan
Prof Atsuo Takanishi

Late prof ichiro kato
WABOT-1 (1973)
WASEDA-Gifu
Wabian-2R
-    Hitachi, walker for elserly and handicapped
-    For designing new prosthetic

Biped Robot that can carry a human – WL-16
Practical Robotic Solutions, TMSUK

Emotion Expression Robot

EYE-Chan
-    ROBOCASA
WK-16

Deformable Face Robot – Solid Works

Flutist Robot for Simulating
-    lung capacity similar to humanresources@paisley.ac.uk

Vocal Humanoid
-    WT-5
o    High speed-camera
o    Vocal cord vibration
o    Kotaro Fukui team

AICHI EXPO 05
-    biggest robotic event in Japan

Toyota robots
SONY HONDA, MITI,

Historical Backgrounds

Simplified history o japan
In 1600s-1867 – Edo Era
-    cultural explosion
-    Japan’s renaissance
-    Karakuri, sushi, manga, ukiyo-e, jabuki, jaiu bonsai, tea cer
-    Karakuri puppels, in 17th C

Center of Education in Edo Era: Terakoya School

Admiral Perry
-    expected japan would take over technology from other countries

populatization of Japanese mathematics
-    Jinkoki, Sangau
-    Pii and proof of geometry, in Japanese templese, 2-300 yrs ago

Astro Boy (1951) manga
Iron Man the 28th (1956)

Left and right brain function varies in part between western and asia

Onomatopeia
-    12000 in japanese, 3000 in English
requiem service for broken needles in japan
-    technology can have soul – need to protect

The ethical implications of automated killers:
Will robots take over the battlefield and law enforcement in the 21st century?
Prof Noel Sharkey

Unded by research council on issues of public concern

Recurrent issue from journalists is robotics and military

Link to police service

Worldwide stock of 6m serice, personal and industraial robogs
Prices falling – 80% cheaper in 2006 than in 1990

Numbers et to rise

US Future combat systems project spending to exceed $230b
-    massive and realistic plans to develop unmanned vehicles to strike form the air, under sea, and on land
-    - congress set a goal on 2001 for one third of operational ground combat vehicles unmanned by 2015

4000 ground based robots in iraq

mostly Explosive Ordinance Deployment

robots as extensions of human fighters
human operators control

UCAV – semi-autonomous
Deployed in iraq
MQ-1 predator – hellfires USAF

Boeing X45A
X47B Pegasus

Robots

US National Research council
‘Navy and Marine Corps…exploit …autonomous vehicles’

Cheaper to manufacture
Require less support personnel
Perform better

Want a single soldier to initiate large scale robot attack from air and on ground

Big IF
-    autonomous systems can identify legality, then
-    let men target men
-    let machines target machines

AI Myth

Grave doubts
-    robots not bright enough to be called stupid

many subtle distinctions to be made in war

cold lead to chaotic or uncontrollable behav

robots do not have t discriminative ability required

Just War Theory
-    fully moral and ethically approp use of mass political violence
-    extends back to st augusiine and Aquinas
-    basis for laws of war enshrined in Geneva and hague conventions

three main parts
-    Jus ad bellum – justifcaiton for waging war
-    Jus in bello – conditions of just war
o    Discrimination
o    Proportionality
o    No means
o    Responsibility

The Artificial Conscience
-    US army funding project an ethical robot soldier
-    Could such a device be more ethical than humans because are not emotional
-    Idea is to provide robot with set of ethical rules to apply in combat situations

Won solve prob of discrim and control
-    used to ally political opposition

John Ford ‘Obliteration’
-    could not possibly protect all innocents in war

answer was to go for technological solution.
Prob of allocating responsibility for mishps to machines

UK Government on Robot ethics
-    horizon scanning doc
-    robots for reproduction, improve themselves, gain AI
-    granted legal rights and have citizen responsibilities
o    voting, paying taxes, compulsory military service

Robot Arms Race
-    once technology developed, everyone will want it
-    DARPA annual grand challenge
-    Singapore, JUK and South Africa started
-    Israel and South Korea have robot  border guards

UCAV
Russian Scat
nEUROn by SAAB

Conclusion
-    if cant guarantee discrim with combatants and innocents, should not use
-    allocating responsibility for killing innnocents
-    eliminating ‘body bag’ politics
-    can a war be just with no danger to one side
-    responsibility as engineers is to be honest about AI

New York Times, 1950
-    ‘…we will need a robot machine commission to function somewhat like our present Atomic Energy Commission…’

Neuroethical issues of cognitive enhancement
Prof Barbara Sahakian

‘boosting your brain power’ BMA publication

do we need cognitive enhancement?
-    Alzheimer’s disease
-    Biggest risk factor, age
-    Each year, 39,400 new cases
-    Current cost of long term care for dementia is £4.6b, expected to rise to £10.9b by 2031
-    Number of people rise from 224000 in 1998 to 365000 in 201

Schizophrenia
-    23m people worldwide
-    even small improvements in cognitive fn could help patients make transition to independent living

ADHD
-    4-10% of all children worldwide affective, most prevalent neuropsychiatric disorder

Ritalin ok for 60% of children

Neuroprosthetics for cognition

Pharmacological possibilities

Foresight – Brain Sciences and Addiction

Use of stimulants by students
-    16% students on some collage campuses in USA
-    See PHOTO

Modafinil improves planning in healthy volunteers

Athlete Kelly White banned

Rights and wrongs of cognitive enhancement in healthy people
-    inceasd performance (boh pleasurable and competitive activites)
-    modafinil
o    Emory University, USA

Questionnaire by Sahakian and Morein-Zamir, 2007

Military, shift workers, air traffic control, school pupils

Normalization removal of nfair disparity in shcooling

Wrongs
-    long-term side effect

Ecstasy and depression
-    Roiser et al Am J Psychiatry, 2005, 162(3), 609-612

Neuroethics socie
Cyborgs…… the future for humans?
Prof Kevin Warwick

Using technology to assist with problems
- parkinson’s disease, DBS

15.20 – 15.40    Audience participation

15.40 – 16.05   Tea

16.05 -16. 30
Panel Discussion – Defining the boundaries to human enhancement: the way forward
Session chair: Prof Andrew George
Dr Andy Miah
Prof Nigel Cameron

My Intervention: Boundaries
PPT on Biocultural Capital

Types of boundaries
- conceptual (defns, aesthetic, cultural, discourse) practical (technical, regulatory, legal, intergovernmental)

Focus on conceptual
- defining enhancements – accumulation of biocultural capital
- EGE Prof outlined egs that were, in my view, sill therapeutic rather than enhancing
- nor Kevin’s Parkinson’s disease patient
- profound reductionism of transhumanism
- reduction of ethics to ‘consumption of ethics’
- trust – crisis of expertise – PEWE indicative of
- how dowe know it’s genuine
- achieving gender equality in debates about enhancement technology

16.30 – 16.45 Audience participation

16.45    - 16.50    Close – Prof Bruce Lloyd

Followed by Reception in the Vaults

Chris Freemantle (2007, Nov, University of the West of Scotland)

Chris Freemantle

Attendance: John W. Robertson, Robert Sutter, David Manderson, Blane Savage, Alison Clifford, Gill Jamieson, Andy Miah

Tags: ontheedge, greenhousebritain, nigerdelta ecologicalinterdisciplinarypractice, sustainability, Scottishsculptureworskhop, celestialceiling, meakinlab, fraserburgh, museumofscottishlighthouses, sociallyengagedpractice

-    arts researcher, producer and fundraiser

Practice Led Programme
-    RGU

On the Edge
-    how and why, rather than what
ME: Cities on the Edge?

Greenhouse Britain
With David Haley, MMU
Impact of sea level rise, resulting from greenhouse
Ocean will rise gracefully and can we withdraw with equal grace

People most disadvantaged will suffer?

What story do we tell?
-    market running
-    wealthy run to high ground

Producer
-    rather than curator )since involves responsibility for a space)
-    rather than project manager (which lacks conceptualize)

fundraiser

Platform (London)
-    social and ecological interdisciplinary practice
-    for 25 yrs
-    hidden rivers of London (Wandsworth)
o    insert micro hydro device in river Wandle (SP?)
•    when tide rise, bell rings
•    electricity from device feeds music room of local school
•    business spin off
-    now focused on ‘90% crude’; Carbon web (structures and influ of oil industry)

Remember Ken Sarowiwa (Nigerian entrepreneur, campaigned about Shell Oilin Niger delta)
-    art work from Sakari Delta Cam –
o    touring sculpture dedicated to him

Aberdeen should be twinned with Niger Delta
-    people coming from oil industry didn’t give value to culture of Aberdeen, since did not regard it as a place of interest

Practice Led Research
-    from looking at visual arts facilities in Scotland

On The Edge
-    from people facing similar challenge

background of Chris in cultural history and theory

Anne Douglas

Scottish Sculpture workshop

Value of contemporary arts in rural area

Series of workshops
-    5 organizations
-    locations
-    research team
-    art SchoolofMediaLanguage&Music

Issues
-    sustainability
o    ME: what is meant by this in rural context?
-    How to write a rief for art project

Projects in Phase 1 of On the Edge
-    Fraserburgh (Museum of Scottish Lighthouses)
o    Engaging young people with comm.?
-    Shetland College
o    Revaluing traditional knitting?
o    Meakin Lab
-    Cullen House and Duff House (fire destroyed painted ceiling)
o    Replace a lost ceiling?
o    Celestian Ceiling (Robert Orchadson painted)
o    Digitsed projection of ceiling which could be projected onto any ceiling
-    Scottish Sculpture Workshop
o    What do you do with a field?
o    What is the point of it?
o    What is potential for organization to work in rural context
•    INTHROW

Suzanne Lacy (Oakland, California)

Artist as leader
She approached Gray’s to do a practice led phd
Author of ‘Mapping the Terrain’
-    emerging defn of ‘socially engaged practice’ (allan kaprov, mary ann Jacob)
She was also a practicing artist.

Oakland
-    ethnic conflict

Background in feminism
-    representation of women in media

looking at young children in media – negative represn – teen pregnancy, crime

growing awareness of young people

each project resulted in major performance , all about dialogue between young and authority, which had been taking place in private and making public so became part of media discourse

mythology of project

she was asked to supervise phd who she couldn’t supervise, so set up process
2 processes, running in parallel
- her work and artists in Scotland

a sort of CPD process

envisaged as 8, but ended up as 15 from around uk

3 seminars
- invited lecture (grant Kesta, Simon Shaik (imagining publics), Tom Trevor (Bristol))

combines arts star, theorist and practitioner
-    circuit of thinking

3 processes of practice based research phd
-    own ability
-    contextualization in other practices
-    theoretical framework

Research Questions
- each seminar examined an issue, which constituted t q

1.    relationship between aesthetics and ethics
-    theorists and critics argued that aesthetics comes out of forming judgements. Habermas – formation of public space and aesthetics that ethics is played out in public
2.    what quality means
-    Suzanne’s practice is necessarily imperfect, due to public form
3.    Power
-    Different bodies involved
-    Trying to create circumstances where young people have a voice

In Mapping the Terrain

Peoples relationship to art work are concentric rings

ME: Matt Barney – interaction between locality and legacy – moving of objects into mainstream art discourse – is there an obligation to relocate art outside of the rural in order for it to overcome its political restrictions -

All Party London 2012 Group (2007, Jan, Westminster)

all party london 2012 group

derek wyatt

- aspiration -create sport think tank
- available pots of money
- XX register
- ofcom

- using lottery tickets
- without a think tank we cannot build the campaign

ATOS ORIGIN, wordwide IT partner

Sponsorship issues, branding issues
Who can associate itself with oly brand

branding issues LOCOG
- discussion about branding expansion – options to be more flexible with non-for-profit orgs

RICHARD CABORN, Minister for Sports

- july 2005
- making the bid orginal – the regeneration of east london, the thames gateway project
- opp: oly park – “the gateway to the gateway”
- 500 acres of park
- environment – sustainability plans -
- terminal 5 – one of the biggest construction programmes in Europe ;
- pressures and issues – media getting more critical, budget controversy, but opinion polls showing increasing support
- visitbritain- new leadership, new initiatives, huge eco impact
- renewing the regions – eco effect
-  uk school games – first time in Glasgow, next time Coventry- 15 disciplines, mini olympics
- UNESCO links
- the 5 boroughs – some of the most deprived areas in the UK; edu opps- employment links
- david lammy – culture and creative advisory panel
-  visit brit
- tessa jowell – eco impact; business clubs around the country
- emphasis on eco impact
•    - 2012 road show – successful
•    volunteering programme – do beyond the CW 2002, not good at after the games, making sure volunteers are taken up
o    how to use oly to inspire people to sustain volunteering interest -
o    see the games as not and end in itself

issues
- eco, tourism, volunteers

seoul presentation line – the paralympics are coming home (first time 1948)
- aspiration – integration oly and para – both groups should come together a bit better than they do now

MANNY LEWIS, LDA

LDS – adquire the land and ensure it is remediated by July 07 and drive the social and eco benefits of the legacy

from the start of the games – key aims
- help produce best quality
- lasting social and eco benefit – emphasis employment and economy

land adquisition
- good news story – we are on track
- 93% adquired, negotiation and engagement with land owner; compulsary purchase order; trying to avoid using it – so negotiation in place

- 66% agreed relocation sites for businesses; business advice and compensation for costs

Legacy

- bigger vision – housing, edu, transport provision in lower lea vlley

- target – 70,000 more people in work across london
- 30,000 to 40,000 new homes
- up to 50,000 new jobs

600,000 million pounds to acquire this land
- it will have much higher value after oly; strong return on that investment

timetable for detailed legacy plan
-

employment, skills and sustainability for the people
- learning n skills council, jobs enterprise, five boroughs are the key stakeholders here – getting them to act jointly
- now setting specific targets and focused programmes
- example – 5 boroughs – employment rate 63% – child poverty;

london employment and skills taskforce for 2012 (LEST)
- impact across london
-
- pre-volunteer programmme
- training 15- 20,000 people to get an NVQ in volunteering to prepare them for Games and work

- London employer accord
- offering interviews to job seekers
- companies involved – AEG, Transport for London,

Opportunities Fund
- 11 million pounds over 3 years from April 03

QUESTION
- technology needs – training people with IT skills
- ref to the new media centre, one of the 5 key physical legacies of the games – will offer a high tech resource for a deprived area

Dianne Thompson, CBE – Chief Executive, National Lottery

nat lot sales on rise, at highest
returned more to soc than any other in world
up 105m pounds on last year
funded over 19b pounds
more than 3b pounds to sport
best medal count in sydney and athens
12 yrs since began
70% of adult popn play
funding 2012:
need 750m pounds, need 2.6b pounds of tickets
if win new licence, she will stay with lottery
first olympic scratch card 3 weeks after decision – fastest selling card since 2002
instant win games online all money go to 2012
36m pounds from OLDF oly lot del fund
‘dream number’
now at 100m pound landmark
raise in effort after 2008 games
qanda
nick woodyle – westminster briefings
how disruptive ciould change in operator be?
a: whole bidding process disruptive.usually diminishes sales, but not for us. decision will be by july, then 18month handover. if we win, then we have to do some changeovers, but so will the other winner. so doesnt make a large difc. transition this time will be more complicated. beijing happens in the middle of this.

derek: i did ask government to withdraw, but was not taken on

q:  regional loss of funds
a:for us challenge is to keep growing funds to avoid depletion. to be frank, will be diffi to ensure, but so far no.

derek: should be a matching funds challenge fund.

derek: dick mentiooned ‘legacy trust’ ofr 40m pounds. legacytrust.org
yorkshire first, timebank, city of london XXX four stake holders.

University of the West of Scotland (2007, May)

2007-05-10, Paisley conference

Brian Boyd

Social Capital and Professional Self-Interest: New Language, Old Motives?
Walter Humes

discourse analysis on public policy

Knowledge, Language and Power
‘Third Way’ discourse
Norman Fairclough ‘New Labour, New Language?’ (2000)
-    tony blair use formations: ‘not only, but also’ statements
Media Promotion of Approved Discourse  – citizenship, globalisation, enterprise, etc
Social Capital – trust, networks, community, identity
-    explain
-    encouarges building of communities

Dominant Discourses
-    origins
-    knowl base
-    political, economic, professional usage
-    explanatory power
-    whose interests are served?

Economic Metaphors
-    knowl as a ‘commodity’ to be divided, packaged and branded
-    knowl as a resource to be owned, accumulated and transferred
-    courses subject to ‘audit’ procedures
-    significance of professionals taking economic metaphors for granted?

‘Social’ Aspects of social capital
-    concern about social fragmentation – lack of respect, decline of religion, instabilityof family, drugs and crime, etc.
-    projects promoting ‘networking’, ‘community’, and ‘trust’ as one response
-    role of professionals in this process
o    have positioned themselves in relationship to social capital – defending the ‘social’

Protean Character of Profesionalism
-    altruism
-    self-regulation
-    autonomy
-    qualifications and expertise
-    status – salaries and conditions
-    self-interest

Funl tensions

manifest in activities of major educational institutions, like EIS
-    also in General Teaching Council

Schools and social capital
-    unreasonable expectations?
o    burden on schools to solve their problems is unreasonable
-    keir bloomer – ‘terminally dysfunctional institutions’?
-    OECD future schoos scenario
-    interrpgating t orthodoxies of professional discourse

Making the Links: the relationship between learning about t Holocaust and contemporary anti-semitism.
Paula Cowan

John Robertson

ME: any research into institutionalised racism?

Interesting to compare these themes with how people remember that year – is there correspondence between what people remember as the most interesting themes and what was actually reported.

Operacion Triunfo: Nation and Television
Fernando Leon Solis

equivalent to BBC’s Fame Academy

national identity never talked about in Spanish media, but in cultural products (entertainment etc)

Product of Gestmusic – catalan tv company (Endemol)- they fought for

broadcast by state-run La Primera

winner repqresented spain in Eurovision (2002 – first seasion of prog)

catalan audiences were same as rest of spain

Alarm Bells in Catalonia: newspaper called Avui
-    eye openers
-    political strategy: homogenizing, centralising, cultural sub-product alien to catalonia
-    reception: catalan audiences were ‘captive’ and ‘lapsed’
o    premise: catalonia is a nation different from Spain

Josep Gifreu (Prof Media, Uni of a Barcelona
-    ‘momentous operation of national integration’
-    ‘a metaphor of Spanish centralist patriotism’
-    ‘a subtle opeation of ethnic-symbolic cleansing in t service of Spain’
-    ‘invisible’ operation

OT as a political strategy
-    Avui’s editoria:
o    ‘a machinery of national standardizatio…it is a Spain which expresses herself from the centre…through a symbolic universe which doesn’t rally exist’
o    ‘process of cretinization’ with t intention ‘to make s more Spanish and better Spaniards’
o    ‘avalanche of rancid Spanishness’ (Jordi Pujol, former Catalan First Minister)

OT and t Captive and Lapsed Audiences
-    ‘Audence behaviour based on dominant references – linguistic, mnuscial, football-related or political…which do not belong to Catalonia’ (Cardus)
-    ‘dependencies that…
-    ‘macro-lie’in whose ‘snare…we fall like idiots’

Cultural Captivity
-    ’71.6% of t viewing share is in their hands’
-    ‘we have an audience which is captive of a foreign media fatherland’ (Cardus)

compare to how catalan’s feel?
-    not easy to claim what catalans think about their identity
-    most are quite happy with duality of national identity
-    1990: people who felt only Spanish much higher

ME: can these discourse on the programme be separated from discussions about constitution?

European Neuroscience and Society Network (2007, Nov, LSE)

European Neuroscience and Society Network
12-13 Nov, 2007, LSE, Regents College Conference Centre.

Launch event

Nik Rose

Aims

Funded by European Science Foundation

‘the new brain sciences’, since 1990s, psyiatric genomics, brain imaging (controversial implications), novel treatments (pharma and brain stimulation)

‘neurotechnologies’

social neuroscience and neuroethics as main areas of discussion

from criminalities to mother love (mother child relationship on brain)

neuroethics is a growing field

implications of some of these developments

neuroethicists have been wary of implications, but neither neuroscience nor neuroethics not been grounded in sound empirical knowledge about what is going on and what would happen if taken outside.

Much of neuroethics has been speculative – slippery slopes, end of free will, working out hypothetical

Aim of ENSN is to find space between social neuroscience and neuroethics – informed debate about realities of neurosciences

Many controversies

‘Today Programme’ this morning – on ADHD and evidence of efficacy of medication

Euro scientists not done much work on empirical aspects of this – mental health

Compare with social implications of new genetics, see how little on neuroscience

Difficult o understand if not scientists

ENSN
-    5 year funding
-    4 themes
o    Neuroscience and Society: setting an agenda for Europea (2007-8)
o    Public Health and the politics of the neurosciences (2009)
o    Neuroeconomies: markets, hcoice and neurotechnologies (2010)
o    Sources of the neurochemical self: identity, consciousness, personhood and difference (2011)

ACTIVITIES

Annual Workshops
-    next, Harvard in May 2008
Network conferences
Short visit and exchange Grants
Rsidential ‘neuroschools’
Publications and communication

AGENDA FOR ENSN CONTRIBUTION TO EUROPEAN DEBATE

Mapping the field
Clarifying key questions for our future work
How to create transdiscplinary debate
Identifying central areas of agreement and dispute
Exploring concepts fo analysis
Developing methods

YEAR 1 AND 2

What are key challenges from brain science?
For research/fnding
Regulation governmenca
Debate and elieration
-    mental health, public halth and social policy, criminal justice system, military, ethics, economies
Considerable decision making under uncertainty

PRACTICAL MATTERS

REGULATION – WHERE FROM, WHERE NOW, WHERE NEXT?
SIMON GREGOR, MHRA, DIRECTOR OF COMMUNICATIONS

Regulation of medical devices

Where from?

SSRIs – 2004
-    timeliness
o    concern that was new info about medication that was not shared as timely as it could have been
-    openness
o    concerned that info had deliberately not been shared
-    willingness to listen
o    lack of.
-    clinical engagement
o    regulators detached from clinical practice

What people think about regulation is vital

‘If I were you, I would not start from here.’

What’s happened with SSRIs is part of a broader part of communication issues

Outline
-    what is regulation all about?
-    Social context
-    Current issues, current themes
-    Where next?

5 years past and forward

What is regulation all about?

What is the MHRA?
-    safety, quality and efficacy
-    but this is not effective way of communicating outside of medical sphere

safety?
-    lay terms perceived as absolute; perception that, once on market, then should be safe to use, but all medicine carries risks

quality

efficacy vs effectiveness not clear either

so, if this isn’t way to describe then what?

Revised language:
-    ‘acceptably safe’
-    ‘no product is risk-free’
-    ‘keep watch over medicines and devices’
-    ‘aim to make as much info as possible publicly available’

taking a different starting point

What is the MHRA?

ALB – Arms Length Body’
Legally, actions of agency are actions of Secretary of State
Funding different:
-    medicines: fees on pharma industry
-    devices: central government funding from treasury/taxation

‘a trading fund’ responsible for covering own costs

Stakeholders?
Public – we take decisions on their behalf
Industry – regulate them and assess products
Government – delegated responsibilities
Academia – conduct trials which we regulate
Healthcare professionals – interface between us and patient

What about NICE
-    imp partner
-    MHRA decides if a product can be sold
-    NICE decides if NHS should buy it.

Facts and Figures
2006-7
- issued 80 medical device alerts
- inspect over 1300 sites in uk and abroad
- received over 800 reports of serious adverse events
- employ about 800 staff
- central inquiry line 45,000 per year

Social Context

Changing environment
-    development in research and technology
-    support innovation without compromising patient safety
Changes in patterns of healthcare and society
-    greater public/patient empowerment and more self-care
-    appetite for more inf on treatments
-    openness and accountability
Changing institutional and international framework
-    new partners in uk healthcare arena
-    increase EU and international cooperation

15 March 2006, Northwick Park Hospital
- ‘drugs victim left like the elephant man’
power of headline
by chance, market research we did on this happened 2 days after this event broke in news.
Worried that this would skew research reslts.
Worked with Mori to introduce indicators to account for impact of this story

Lunch

THE NEUROCHEMICAL SELF AND SOCIAL INEQAULITY: A NEW FACE OF NEUROETHICS
Alex Mauron

‘Wha makes health a really imp social indicator is that psychosocial risk factors for disease reflect how we think, fel, experience and suffer our lives’ ‘Richard Wilkinson 2005. He impact of inequality: How tO make sick…

‘I shall argue that the brain is a crucial organ in generating the social gradient in health’ ‘Michael Marmot ‘ Status Syndrome’

how it reflects inequalities

There is a social gradient in health, which is largely caused by social inequality.

Universal Ineqaulity

The Whitehall studies

Longevity and several other measures of health are socially stratified
One lives longer and healthier lives at the top of t social ladder

Not an ‘us vs them’

-    not Marxist social class!!!

More Gradient like

Cuts across all societies

Marmot shows tha differential between social class remains, but those who are in lower class have been catching up

Drever and Whitehad 1997

‘Educational ineqaulites in life expectancy in the German speaking ar of Switzerland between 1990 and 1997: Swiss National Cohort[
-    ed achievement good indicator of social stratification

The pecking order
-    disease and premature death more prevalent in lower part of social ladder
-    not matter of material circumanstances or acess to medical care
-    in fact, if healh outcomes in Whitehall are corrected for health behaviours (smoking etc), gradient gets shallower, but remains
-    relative social status is what counts (in affluent societies), not abslute standards of living
-    life entails series of more or less stressful transitions and lower you are on social ladder, the harder you are hit at each of thesw

not inevitable

hierarchies are inevitable, but how they translate into inequalities is the question

A steeper social gradient makes things worse for society as a whole

Once counry or region ot of povery, further increase inaverage income no longer good indicator

Wilkinson 2005 – ‘life expectancy in relation to living standards in rich and poor countries’
-    in poor countries, small income increase buys a lot, but once passed, things more complex
-    looks like need to spend more and more money to get marginal benefit
-    no obvious logic between more affluent variaion in life expectancy

led to investigation of effects of inequality

Ross, Wolso, Dunn ‘Relation between income inequality and mortaliy in Canada and in the United Stats cross sectional assessment using census data and vital statistics’, BMJ

While US is highly unegalitarian, is variation

Trying to explain this variation

Wilkinson 2005: ‘the effects of income inequality (left-hand side) on social and psychologhical well-being 9right-and society)
-    highlights relative poverty, early childhood, social status (comparing ourselves with others), less trust

more inegalitarian societies tend to have worse health outcomes, due to multiplicity of factors (violence, less social capital, more chronic stress for more people)

Turning biology on its head: social causes, biological effects

I was formerly a molecular biologist

Other factors from Wilkinson include stress, deprerssion, etc

In discussing inequality and biology, must cope with social Darwinism and eugenics.
And because of this, have been confined conceptually ie.
1.    either biology is there to provide t ‘real’ explanation of social phenomena, or biology is largely irrelevant o social sciences – I think this is rong
2.    Either inequality is largely biological and there is nothing one can do bout it or inequality is largely social and social reform is possible –

In either case, third alternative ‘tertium datur’

Is thre a pilot in the plane?
-    connect mental states with biology

Social Darwinist tradition assumes that bilogy more ‘basic’ than social, so more likely to be causal

But this is wrong

Causation has no a priori direction

Iological and psychosocial equally worth investigating

From social causes to biological effects

Different hypotheses about causation

1.    Being in poor health leads to being at bottom of social hierarchies
Variant: being poor leads to poor health
Variant: poor lifestyles lead to poor health eg. Poorer people smoke more, etc

2.    being at bottom leads to poor health and shorter lives

each true in some sense but main message is that, at populaion level, number 2 is more prevalent

suggestive evidence from primatology

Sapolsky: hierarchies in several species of monkies and apes have major effects on longevity

Low status baboons don’t smoke, eat hamburgers, or fail to keep appointments with their doctors; high-status baboons don’t read t health pages of t NYT or elong to fitness clubs’ (Marmot, 2004: 83)

Thus, ‘blame the victim’ mentality – eg. ‘doctor I’ve got brain cancer, what did I think wrong?’ – fails at first sight in non-human primates

Also, if look at biological pointers to hierarchy induced stratification

Stress: one of oldest and most successful links between physiology and behaviour

Hans Selye (1907-1982)
-    ‘general adaptation syndrome’
-    ‘flight or flight’
-    hypothalamic pituitary axis

Roger Guillemin (nobel prize 1977)
-    discovery of brain hormones

hippocampus
-    memory, stress response, depression, neuronal regeneration

psychology
-    stress and coping
-    loss of control ‘learned helplessness’
-    social connectedness
-    self-esteem, social inclusion and exclusion

evolution
-    why was early human sociality =more egalitarian. Why did agriculture hange that?
-    How was evolution of cognitive capacity linked to sociality in human evolution?
-    How are we to understand t evolution of language in relation with sociality (language: a more efficient equivalent of grooming? Robert Dunbar 1996)

Synthesis of Stress
-    physiopathology
-    sociology anthropology, econmics
-    molecular endocrinology
-    epidemiology
-    neuroscience, cognitve psych, primate studies, evolutionary psych

biopoliical consequences
-    worrying about inequality ot of fashion in affluent west
-    worrying about health is central concern of modern mankind
-    inequality as public health concern will be heard, where inequality as a matter of social justice may not

but is this merely a tactical issue?

Healh embodies essential ethical values

Neuroscience of healh provide new language in ethics

New face of neuroethics
2 classical faces
1. ethics of neuroscience (ethics of neuroscientific expermentation and progress)
2. neuroscience of ethics

now a third
3.    neuroscience of equity: exploring how social structures impinge on health and how this exploration inspires ethical and political reflection on how can redefine them to lead better lives for more people.

THEORIES OF PERSONHOOD: BRAIN, SELF AND BEHAVIOUR IN CHILDREN WITH ADHD
Ilina Singh, BIOS LSE

Nurture-neuroethics: a contemporary intellectual and social ethos

Evaluating potential harms of psychtropic drugs against backdrop of assumptions about:
-    what child is or ought to be
-    childrens capacities and needs
-    good/right childrearing practices

often involves a lot of paternalistic practices

highly gendered

can contribute to reified scientific understandings of ‘the child’
-    genetic, biological, evolutionary acconts of behaviour, risk, capacities, outcomes

focused on genes and criminality

children don’t have a public voice, since assumption about their needs

FDA now mandated pediatric 6 month extension for new drugs, but unlike mandate for genetic, neuroscience research from NIH does not have an ELSI arm

Bioethical concerns about use of psychotropic drugs with children
-    threat to personal autonomy and free will
-    undermine personal responsibility
-    undermine ‘right to self-creation’
-    threaten t ‘character of childhood’
-    undermine personal authenticity
o    sense of self’s uniqueness and desire to be true to this self (Charles Taylor)

a embedded ethics approach (evidence base)
- what are children’s experiences of diagnosis and treatment?
- are ethical concerns about potential harms t right concerns?
- what are t consequences of new biomedical interventions as these are expressed ‘on the ground’?
- contributions to:
- evidence base for psychsocial and ethical side effects of biomedical intevetions
- understanding dynamic associations between neurotech and self etc

Project involving children with ADHD
-    2004 UK invu sudy with children taking medication for ADHD (20 boys, 3 girls)
-    2007 UK study commissioned by NICE. Focus on boys and girls 9-15yrs. All taking stimulant medication for ADHD, 17 children)
-    2006-2011: Wellcome Trust syudy up to 100 children in US and UK
o    so far, uk children taking med for adhd

poss that results don’t isolate effect of medication

what role does the brain play in behaviour?

Assumption that taking psychotropic drugs will effect how children think about themselves, eg. Authenticity. Is this actually true?

1.    Theory of nerves (not the brain)

Some children think it has nothing to do with brain

ME: where does the child get the language for this? How are they explained what happens? What are these children explained about the drugs?

2.    War Theory

They draw pictures of chemicals fighting in brain

Children don’t exclusively attribute inability to concentrate on chemicals. They use explanations strategically eg. Using it as an excuse. They also say parents and teachers do too

How important is your brain to who you are? (‘self’)

Story explaind to children where brain replaced by dwarf
Not one child has said would accept different brain
Reasons:
-    could be worse off
-    might not recognize friends and family
-    memories most salient loss
-    memories make the person

thus, memories, rather than behaviour define self more

Is taking medication like getting a new brain? (becoming a different person)

Children ambivalent on this.
Times when clearly no, just helps behaviour.

But, same children will vary in answer and sometimes say yes:
-    ‘I hate that it changes me’
-    ‘my friends like me better when I’m off the tablets’
-    ‘I’m still me, I’m just not as much fun’

Relationship between behaviour to self?

Child shown a picture of a child that looks scruffy

Stable characteristics of the self

Behaviour is sign of core, evil ‘I’ (dimension of self)
-    more salient in boys
-    where does idea of core bad self come from? Does it pre-date ADHD diagnosis and medication?
-    How is belief related to self-esteem and self-perception?
-    ‘bad boy’ dimension has social status and value

sounds terrible to say ‘I am evil’ but I’m struck by relative lack of concern by this

instability of behaviour

consistent reports of core bad self
consistent reports of instability of bad behaviour

majority of older children experiment with their medication eg. Decide whether to take meds or not. This is a way for them to sort out who they are.

Children’s experienced agency over their behaviours could over time unsettle notions of core ‘bad’ dimension of who they are.

But…core, stable dimensions of person are hot topic of research in developmental psychiatric genetics
-    focus on children with behav disorders, eg. ADHD, CD, ODD

childhood behav disorders, genetics and criminality
-    continuity
-    genetic risk strong association
-    imaging studies show similaries of brain with children with conduct disorder and adult psychopaths
-    genetic risk factors discovered as well (Viding et al, 2005, 2007)

genes, behaviour and persons
-    tes of genetic model: DNA database, genetic pellets, shared automated patient medical records systems, mental health screening
-    prediction of criminality at indiv level is poor
-    genes small effect

productive nurture-neuroethics
-    involve children as participants in research
-    also as agents

Q&A

Q: benefits and harms of psychiatric categories

Nik Rose: ‘interactive human kind’ – notion of self inextricable from self. In Alex’s argument, grounded in animal models, as if stress is a given. But illina’s saying could not be explored in an animal model. So, comments on limits of animal models.

Alex: epistemic of animal models different from what illina was saying. Sort of animal experimentation that comes to mind, brings up preformatted questions. Can there be an animal model for what this pill cures? In my case, thre isn’t prepackaged q about animal model. Interest for primate sties by social epidemiologists much more haphazard. Reason for why they became interested in primatologists, is because were phased by question of causality. Mounting confidence of comparisons, since correspond to physiological and mental functions, where enough affinity between apes and us to believe they are explaining something. Since you are a sociologist, I assume you raise a point about contingency.

Q: memory most salient part of self, rather than behavior, but final part of your presentation, concept of bad self, you presented it as a behavioural thing.  But I thin that if memory is more salient, memory of bad self is also important.

Paul Martin, University of Nottingham: ethics – commonalities on issues of political, ethical of disease aetiology. Is there an underlying ethical concern that this meeting is about?

Illina: where are places where children will be made vulnerable and exploited? Trying to ask whether is happening around Ritalin. I’m not sure that it is. My intersection with Alex is in ‘poor children’. Largest proportion of Ritalin are children in foster care, many of which are from ethnic minorities. So, are  broader questions related to social justice. A sociology of psychiatry.

Alex: my ethical agenda comes fmor paradox: discourse of economic efficiency that values inequality, sees ego challenge of keeping social status, buying status, all good for economy and other voices that inequality makes us sick.

Simon Williams, Warwick University: as a medical sociologist, broader debate about inequalities in health, psychosocial pathways, neo-material factors, critique of stress-related research, Marmot and Wilkinson criticised for looking at consequences rather than causes of inequality. One debate is neo-liberalism cause of inequality. Recognize that material factors do play a part.

Alex: v important ongoing debate. The left-wing critique to Marmot and Wilkinson. This works function is to provide more sophisticated diagnosis of what happens. Mapping onto history of medicine, this is best of 18th century medicine to make sense. Then a pathological science in 19th century. This is not a critque of work, but xpansion of work programme, upstream into social causes.

Andreas, Aarhus Uni….: inversion of causality. Push argumet, change in biological measurement is index?
AleX: yes, you are reformulating my implicit message. Frustration of tradl public healh specialists who, maye 50yrs ago, attacked great public halth problems with missionary spirit and thought that preaching would solve problem. Only so much can do in encouraging people that ar managers of own health. Priest doctor has reached lmit

Q: Alex, programme of activism towards more equality. Relationship between research on neurotech and psychtherapeutic position.

Alex: wrong to imagine a political programme distilled in semi-automatic way in consideration of facts, but some conclsions are quite straightforward. Eg. Stress pathways play major role, they are held by early childhood. So, trying to mitigate against inequalities in childhood, seems a good place to start. Beyond that, more difficult to be precise. Prior step is to identify what makes being in a relatively lowly position in affluent societies, makes one miserable. This precedes policies.

Illina: I certainly have an agenda for clinical work with children who have behavioural disorders. Depends on which regime. In America, must be talking to child, but often child is not involved. In uk, more multimodel diagnosis for behav disorders. Also danger of that disappearing because of lack of understanding.

Break

THE GLOBAL NEUROTECHNOLOGY INDUSTRY 2007
Zack Lynch, Managing Director, Neuroinsights (San Francisco): Executive Director, Neurotechnology Industry Organization (

Neuroinsights – leading market research and advisory company

2 publications

neurotech industry report

“Neurotech Insights”

host annual conference. Investment and partnering conf

what is the neuro industry?

Neuropharma (cogniceutical, emoticeutical, sensoceuitical)
Neurodevice (neuroprosthetic, neurostimulation, neurosurgical, XXX|)
Neurodiagnostic

2007 – $120.4b, 10% growth

individuals afflicted – 2 billion (largest) sufer from brain related illness
-    highest is addiction, then anxiety, obesity, sleep disorders, alzheimers, epilepsy, etc etc

brain related more losses than any other category

world economic burden is $2trillion

in 2003, American Cancer society identified burden as $172billion, diabetes $132b

brain is $1billion

NIH neuorscience is similar to cancer, but burden is 6x higher

Human genome projec success has helped

Neuroscience
Bioscience (genetic engineered animal models, stem cell)
Info Science (Brain processing)
Nanoscience

Impact on neurotech clear when looking at pattern trends

Neurotech Innovation Accelerating

From therapy to enhancement

Therapy, enablement, enhancement

Enablement implies lifting up from bottom, implies empowering

Nearly all neurotechs are not enhancements, but enablers

Goals of neuroenablement?
-    Cognitive (faster learning more rationale decision making, better memory retention, more focus, smarter)
o    ME: if this is not enhancement, what is?
-    Emotions (higher/lower arousal threshold, more/less control/)
-    Sensations

Athletics
Cosmetic Surgery (150% increase in 5 years)
Competitive Advantage

ME: they looked like enhancements to me.

Future of Business: Neurocompetitive advantage
-    mental health ultimate competitive resource
-    neurotechnology increases worker productivity
o    increase memory retention
o    decreasing anxiety and stress

cultural concerns over naturalness will influence ethical debate

reality is tht we live in a competitive world

if a few people use it, then will change for rest
one of first industries to be affected will be financial model

currently based on assumption that people are rational actors

new ethical and legal challenges
-    national security vs indiv privacy

how will indivs who consciously shape their neurochem perceive…
-    each other
-    family relationships
-    political rhetoric
-    economic outlook, consumer confidence
-    cultural norms

as indivs tone down fear, this can affect which policies become implemented

postindustrial and postinformational neurosociety is imminent

THE BIRTH OF NEUROECONOMY
Phillippe Pignarre, Uni of Paris

Not sure of meaning of neuroeconomy
We should give meaning to this word
Problem is manner of
Foucault ‘the XXX function’
Particular commodities, professions, and

Beginning of chronicity

History of psychiatry

1880

bruno latour
-    should never give general reasons power to explain
-    proposes shift from socio of durkheim to Gabrielle XX

psychoanalysis suited to needs of community in transition

decline of psychoanalysis

psychpharmaceuticals

Ludwig

Deleuze and guattari – use ‘machine’ in same way – machine is always in interaction with other machines. Eg. Technical machine of factory, interacts with educational machine, marketing machine etc. (from deleuze)

So machine of pharma interacts with machine of industry?

Take proposition of machine seriously not just as metaphor

Produces ‘light biology’ – sum of tes concerneing living organisms. Eg. Dopamine.

Andre Lakoff – ‘The Pharmecutical Industry’ – Cambridge university

Deleuzian machine move away from neuroeceonomic determinism

Ian Hacking – metaphor of ecological niche – transient mental illnesses –

Can have much wider use

Q is what makes some possible and some impossible

Oblige us to find mechanism that explain how something works

Q&A

Answer: modafinil, bringing up to capacity of the highest performers

ME: so, this is raising to the highest range of normal functioning, but including the highest percentile, which is, quite often, a dysfunction.

Philippe: prozac – better than well – not similar to traditional anti-depressants, more like cocaine. 2 risks of proposition is 1) invent cocaine (which already exist) or 2) Lisenco? How to solve political problems with science (solve problem of countryside, agriculture, USSR in 1930s with technological dreams)

Q, Max Plank institute in Berlin: comment – epistemological –

Q: enhancement or enabling applications? Are they afraid of bad publicity, since public is not wlling to accept? Is public opinion likely to change? Or are they going to invent new disorders?

Zach: strong marketing behind this yes. Creating new markets. Slicing and dicing old definitins to sell new things.

Q: nanotechnology – many claims and hopes v similar to ones you’ve mentioned, but difference is that also discussing difference with therapy and enhancement. Didn’t mention enablement. Didn’t really talk about targeting brain specicficaly, but had idea that could target part of body without going through the brain. Is there any convergence from nano with neuro?

Zach: nanotech is fundamental driver of neurotech.

Nik: might be in sitn of ‘either, or’. Either huge burden of mental disease, social economic problem, investment is ethical imperative. Or, find new way of medicalizing marginal conditions, new marketing to generate investment, claims overblown, bubble will burst. If stuck in either or, then don’t advance argument easily. Philippe mentioned ‘Hacking’s notion of marketing for disorder. Just because a niche, doesn’t mean don’t suffer from it. Path dependent theory of truth – investment forcing things into existence. Plea to ask whether way beyond either or. Chart out empirically how things are happening.

Philippe: the drugs that don’t work is mos extraordinary possibility. I

Lindsay: Philip Merton – sociology of expectations – economy of performativity – hype has a market value – do you look at genetics market as cautionary tale – burst bubble of genetic biotech –

Zach: no. venture conferences, analyzing industry. Stock indexes, networking opportunities. If we are lucky enough to have a bubble in some years, tht’s good.

World Anti-Doping Agency World Congress

WADA World Congress

Jacque Rogge

Not just about elite sport

‘it is a public health problem
-    ‘high school and university sports programmes’

‘hundreds of thousands of teenagers’

‘general sporting public’ – recreational

EU report doping risen from 5% to more than 20%

Raw Deal

Richard W. Pound

Joining of sport and government

WADC

Minister of Education, Spain

New Spanish law this year

FINANCE

Craig Reedie

Wada history

1998 – festina scandal at tour
1999 – world conference, Lausanne

Foundation under Swiss Law
Foundation board of 38
Executive of 12

Healh, Medical and Research (Ljunqvist)
-    List
-    LAB
-    TUE
-    Gene Doping

ME: where is Ethical Issues Review Panel??

EDUCATION

Presentation

Questons

Lunch

MEDICAL

Arne Ljunqvist

Key outcomes of research programme

Anabolic Steroids
-    disocery of desoxyMethylTestosterone
-    detection of 6 oxo compounds
-    method of detect aromatase inhibitors
-    devel of CRMs for steroids
-    proof of conversion of supplements into nanrolone
-    detection of new long lasting metabolities
-    genetic and ethnic differences in adrogen excretion
-    devel of in vitro syst to identify AS

Blood Doping

Third gene doping symposium in 2008

Food supplements
-    if needed, why? If irregular food intake, should correct.

Even within same bottle, some pills have banned substances and others not.

David Howman

160 tests of Marion Jones – not one adverse finding

Operation Gear Grinder 2005 – mexico

Doping and Public Health (2007, Aug 15-16, Aarhus)

Doping & Public Health
Arhus, Denmark, 15-16 August, 2007.

15 August 2007
10.15 – 10.45
John Bale and Richard Peel (Chairing sections)

Prof. Jens Evald, Chairman of Anti Doping Denmark – Introduction: Anti Doping Denmark’s Action to Protect Public Health

Prof of Legal Philosophy at Arhus.

background
doping and fitness
public health
fitness-doping
anti-doping denmark 3-year project

Background
Anti-doping denmark – independent
Act of Promotion of Doping-Free Sport (2005)
-    ADD is self-governing
-    12 member board
-    7 secretariat
-    ministry of cult = 1/3 of budget

Act 2005
-    doping control
-    info
-    research and development
-    international collaboration on fight against doping
-    provision of advice

Section 9
-    fight against fitness-doping (ie. doping use outside of sport.
-    requires implementation of WADA code in gyms.

Gov argument for fighting doping
-    public health
-    illegal trafficking
-    risk fo drugs spreading to organized sport

Public Health Issue

night-life violence increases by doping

effects of doping:
loss of interest in surroundings
social isolation
suspicion and jealously
new friends with own language
dress code and social code
can’t see anything wrong with own behaviour

big confidence
agrresion
depression
alarm
change in personality
lack of empathy
increase sexual self-orientation

how do users see these changes
- problem is that they do not see the side effects (ME: AS PROBLEMATIC)

ADD a ‘natural born’ protector?
- was never asked to form.
- today, have 70 of 450 centres in system
- working towards new model where commercial centres part of org

ME: is not talking to the political economy of doping (in Denmark). Like the dopers, is unaware of the context of own behaviour.

Is fitness doping a big problem?

Alesandro Donati wrote the WADA report, estimating doping on global scale
- the report mentions 15,000 abusers, the newspaper says 31,000

84% of sold growth hormone is used in sport
ME: but I thought many people believe most athletes are not using hgh, so where is this being used across sport?

also test for doping in prison – the prisoners trust us.

of tests:
0.6% positive in DIF
10% positive in DGI
20% positive in commercial fitness centers

number of positive tests has increased, but could be because of more effective testing.
(testing for steroids/, not social drugs)

some people talk about 60,000 abusers in denmark. we don’t know.

ME: what could improve knowledge. WADA talks about intelligence. it’s interesting for me to hear you throw out the 60,000 figure, given your own estimates. are there formal mechanisms for gathering intelligence and are they different from WADAs? come to think of it, what are WADA’s mechaniss?

Questions:
-    is ADD the right body?
-    Is fitness-doping a real problem to society?
-    which drugs should it test for?
-    can we accept social isolation of doping users?
-    what is lacking the most in fight against doping?

ME: what is worrying about isolationism of dopers? There has got to be at least two more premises to the argument.

ME: the fact that he is asking whether we test for social drugs is v problematic.

Questions and Answers

J: problem is that we cannot register the names of people.

Changes in WADA code allows making separate rules for fitness centres.

10.45 – 11.15

Asst. Prof. Paul Dimeo – The Public Health Origins of Anti-Doping

Key historical moments
- 1948: Dr Christopher Woodward raises concerns about cyclists’ use of drugs
- Late 1940s/early 1950s – returning war verterans and wide availability of amphetamines contribute to rising usage at all levels of American sport
- 1952 – WHO conference
- 1957 – AMAconference
- 1960 – death of Knud Enemark Jensen at Rome Olympics, attributed to amphetamine abuse through later investigations dispute this claim; Avery Brundage raises issue with IOC; British anti-doping expert Arnold Beckett claimed later that IOC knew about t widening use of steroids by 1960
- 1961 – British athlete Gordon Pirie publishers a book ‘Running Wild’ in which he claims some British, many American and many society athletes use doping drugs
- 1963 – CoE meetings
- 1964 – International Congress of Sport Sciences meets during Tokyo Games and prob of doping is raises, also exptl testing conducted on cyclists during Games
- 1967 – British Association of Sports Medicine conf on doping held in London
- 1968 – first testing at Olympics for amphetamines; test for steroids  would arrive in 1076.

(Dimeo, P. 2007. A History of Drug Use in Sport, 1876-1976: Beyond Good and Evil (Routledge))

between 1950s and 1960s, change in anti-doping
postwar period public health movement
questions about how sport played a role in public health
by late 1960s as sports orgs took control, tone of anti-doping changed to defensive of sportin culture and assumption of sport ethics. doping not defined as prob of too much intensity, but as a bleamish on utopia of sport. consequently, for public health officials who were more objective on health, had been lost. chance for moderation had been replaced by fanatic approach to the problem.
beginnings of shift from 1952 Februrary.
IOC had announced in 1933 that it did not like doping, but did nothing until early 1960s.
were not many instances at this time.
1948 Woodward
1949 italian ctyclist died allegedly of amphetamine
in US groupwing prob
first major statements on doping came from health not sport – WHO 1952
- 2 speakers talked: Carl Evan – Norway health – oppressive system – said ‘use of dope….popping up here and there in the amateur sports world….will be a disaster for sports’
- American colleague at the conf: Milton Lomer – Social and occupational health secretary for WHO, didn’t like look of sport – athletes pressured into taking health risks for national prestige. he saw sports in critical terms. he thought sports were to blame.  not clear how these speakers reflected view of WHO. no further action was taken.
June 1957 – AMA initited research studies on the subject. beginning of surveillance process. Herbert Berger narcotics expert – claimed dubious success of 4 minutemilers, but also critical of amphetamine use in college and high school in usa – widespread pattern of drug use ‘shocking and visious’ – saw it asa  public health issue. ‘drug addicts might get their start taking amphetamines in high school and college’. also said users displayed violent and criminal behaviour.

anti-doping among officials at this time
AMA projects on use of amphetamines another was a clinical study about effectiveness of amphetamines for performance.

this affected publich health stratgies of surveillance.
clinical studies were sign of honesty – though sports authorities discourages research on doping in 1960s.

in public health cntext, concept of fairness not visible
if anti-doping had remained focused on public health, then nature of antidoping would have been v different.

early 1960s, in UK Austria,
BASM and itlian counterpart established positions
CoE defined doping as an evil, such a view had become routine
like a religious doctrine
eg. IOC anti-doping Arthur Poierot, also Sec of BASM, in 1965: ‘doping is an evil. it is morally wrong…legally indefensible’. – at this time, no evidence to support any of these points
eg. XXXX immoral act of doping  ‘keep the ideal of sports pure for the welfare fo all mankind’

testing in Olympics by 1968.
guardians disliked modernity in sport – eg. training technology.

no interest to dialogue values
problem in their view was fringe element of sport ‘cancer’ on utopia of sport.
IOC wanted elitism, but with amateur values.
constructed a sense of sport that focused on excellence, but values that ddi not reflect reality of elite sports – inspired by indiv and national glory

how ddi early public health experts compare with later sports colleagues

similarities
both disliked drugs in sport, though for different reasons
both thought monitoring important

differences
if about health , not ethics, then must consider broader public
eg. alcohol – all allowed to drink alcohol and excessive can do, but if drive drunk can be prosecuted since affects others health. other crossovers – approach to alcohol has been realistic pragmatic and yet allowed freedom.

if sports doping had been seen purely as public health, would it  have emerged

ME: hmmm, medical intervention of doping might be a difference?

11.15 – 11.45
Prof. Barrie Houlihan – Doping, public health and the generalisation of interests

how politics is changing and how it might change.

theoretical presentation

theory of policy change

generalizing interests – building alliances with sympathetic policy areas

domestic and international policy making is hotly contested – many polic leaders are under constant pressure to give prominence to their issue and to protect it from others

2 questions:
- how can momentum and commitment to resources at domestic and intenational be maintained?
- to what extent can domestic and international sport interest control discoures….

Anthony Downs – policy ‘life cycle’
-    pre-problem stage
-    alarmed discouvery and euphoric enthusiasm
-    realizing cost of signif progress
-    post-problem stage

much of history of anti-doping follows this pattern

first stage
-    death of Tommie Simpson
-    withdrawal from 1983 Pan-American Games
-    1988 ben Johnson
-    1998 tour
-    2007 tour

each began with enthusiasm which rapidly dissipated

look at discourse that surround doping

3 dominant discourses
- fairness, health of the ATHLETE (not public health), image of sport (role model, etc)

these are generally self-serving, inward looking and politically naïve

WADA Code reflects mixed rationale
-    concern limited to athlete’s community

however, wada needs governmental allies
examine how these other orgs discuss doping – they use broader, social terms
eg. CoE – sport important role in protection of health, moral education, international understanding; EU – competence in area of public health; UNESCO Convention – education, health, development and peace
many govs have publich health emphasis on sport – France, Norway, Sweden, Denmark

Dick Pound – ‘unviversal recognitioj…doping serious threat to public health’

whether it’s being exploited, I’m not sure

but not only discourse

competing discourses:
-    constitutional: sport should be self-governing
-    criminal: doping is big criminal business
-    workers rights: right to eran leaving
-    moral/ethical: fairness:
-    medical: health of athletes, treatement
-    public health: doping spills into non-sport

constitutional, moral medical are most promiinant international, others vary between countries

WADA’s response?
-    is WADA aware that it is competing?

public health not exploited by sport

1998 – watershed
- showed weakness of ‘constitutional discourse’
- French gov intervention (and criminal discourse)

Continued discuss about criminanlization
need for sport to build a defensive ‘generalisation of interest’?

criminalization – ljunqvist – advocates criminalisation of sports related drugs

strategies for generalisation of interests
-    sectional interests (like elite sport) aim to further interest by linking to public good o
o    ‘one has to hrase one’s argument in impartial terms, as if one were arghing for the public good and not fornes own self interest’ (John Elster)

is linking elite doping with public health going to strengthen elite anti-doping?

back to initial 2 questions

discussions
-    what is existing relationship between antidoping and external interests?
o    what evidence is there of alliance building?
o    the evidence suggests that they are not.
-    are we seeking generalisstion of interests by sport to link with supportive external interests or the incorporation of sport by eternal interests.. – rather public health sees sport as valuable to them.

ME: is this because it would diminish the autonom yof WADA

parallel discourses?
-    internaitonl, still focus on athlete’s health, modest concern on public health and broader pro-social discourse on sport
-    domestically: increasing number of countries a crime/law and order discourse (encouraged by WADA?) but in others an increasing concern with public helaht and sport for al not just elite)

evidence of a changing discourse? sport still claiming tis privileges status (overplaying its hand)
sport/elite soprt has lways been linked with other non-sport interest

ME: how does this function with doping technologies that are not clearly linked to public health issues – e.g. blood doping or hypoxic training? Is there a challenge over boundaries – ie. doping more than drugs. difficult to excite public health policy makers about hypoxia?

ME: would a public health approach require the separation of some doping technologies from others? – ie. some have a clearly larger spill over than others.

what will keep doping on the front burner?
rely on continual succession of crises?
criminalization is easier than public health.
links to either run risk of loss of control by WADA and NADOs.
but criminalization makes more difficult harm minimization.

Verner:
don’t know if prob of doping, but we’ll solve it
in 1960s don’t know if was a big prob, but begin to solve
how politicians trying to solve.
problem generated by political ambition.

ME:mobiilisation fo anti-doping is often

Barrie: different to identify public health dimension of some doping technologies, but for others, it is clearly the case

11.45 – 13.00
Lunch
13.00 – 13.30
Prof. Claudio Tamburrini – Postponing motherhood: an unfair advantage?

follow up project on genetic technology and gender

trying to ascertain how genetics impact on gender equity in elite sports

from time to time here that women give birth after menopause.

none of the techniques to assist this are genetic, but is conceivable.

whether athletes who postpone motherhood gain advantage over those who don’t?
is this adv unfair?

when we speak of motherhood, not suggesting htat elite sports are not compatible with motherhood. some argue that it eventually enhances sports participation. (IRSS 2001).

but still the case that natural difference between mean and women still exists – women bear children and men don’t. so possibilitiy to equalise ability will remedy natural disadvantage.

do not take a stance on whether interventions aimed at delaying menopause should be considered treatement or enhancement.

does postmenopausal….

assume that gender equity is desirable, though this is contested by some.

possible that technology could create more gender equity.
-    eg. resistance to ART – reinforces idea that women should become mothers and limits value of fulfilment without children

Laura Purdy

even if decision makers accept homosexual families, better heterosexual since discrim, but this is not a good argument.

develop a ‘happy child’ criteria – but no reason why could not meet standard

reasonable happiness

postmenopausal motherhood discourse shows resistance.

lets assume many women will do this. impact?

change of family. but no harm in that.

assume that once mothers, will shortly die. need to ensure provision within the community.

no reason to oppose postponing motherhood.

perhaps the children might resent older mother.

sport obvious eg where having children is a disadvantage.
-    those who do not can remain productive during  their peak years.

is genetically postponing motherhood unfair in elite sports?

a substance or method will be considered if 2 of 3 conditions.

assume that the technology will become safe.

is it an unfair competitive adv?

if open to all, then how unfair?

perhaps expensive will create greater unfairness?

not suff reason to label it as unfair, according to anti-doping policy.

trying to underline sport governance of such mattes, when the become a scientific reality.

must search somewhere else to discern whether is unfair or not.

might argue that is unfair adv since put colleagues under tpoo heavy burden – renouncing to motherhood for the same of competitiveness

but all sports persons forfeit plans and put pressure on competitors to do the same.

perhaps the too heavier burden objection could substitute the current criteria, combined with some other form of consideration. eg. ethos of sport – rules out improper manipulation of the body.

ME: What sorts of things are able to become proper manipulations of the body?

hypoxic chamber might be risky if stay in too long, are directly enhancing, but unlike trad doping re ot seen as artificial.

prob is how the competitive adv might be seen by sports bodies.

given that men are fertile for longer than women,

ban on gene doping – what is the non-therapeutic use? possible to treat muscle disorders that might improve muscle strength.? gene encoded epo to boost bone marrow, might also increase for sport.

must be more accuratey specify unapproved aplpictions of genetic technologies.

need increased insight on potential conflicts between socially desirable goals and ethos of sport.

need for open and critical debate on how governing bodies should deal with people who are already modified.

the greater the possibility of other genetic technologies to equalise different, more reason to accept

13.30 – 14.00
Prof. John Hoberman – Is testosterone a supplement or a drug?

20 years ago. West German scientists Manfred Donicker said steroids should not become a popular nutritional supplement

2 months ago in Las Vegas – Intenrational Society for Sports Nutrition
- middle aged man on testosterone on prescription.
- he said, any man over 50 who is not on a testosterone product is crazy.
- ie. donicker’s fear hass come true.

we are talking about a contest between testosterone status

what is difference?

supplement

assume fewer regulations, since assume fewer risks

I will argue that, in order to understand this, must look at history of synthetic tesosterone and realise that campaign to market to the masses

ME: big deal.

Time Magazine
sept 23, 1935
“german and swiss chemical laboratories are already prepared said Dr Ruzicka [one nobel later] last week, to manufacture from sheep’s wool all the testosterone t world needs to cure homosexuals, revitalize old men”

our society has imagined testosterone being put to public health use from the beginning

Newsweek Sept 25, 1996? ‘ Super-hormone hterapy’ ‘tesosterone’
(Uses same cover as john’s book)

Time Magazine – tesosterone again in Time Magazine

The Early Androgens Market: How testosterone did not become a ‘tonic’

there is no critical distinction

Androgen Ointment for careful dosing (1939)
- testosterone drugs being tested.

[see presentation from September 2006 in Newcastle]

Testosterone for Women: the new era of sex as a lifstyle entitlement

Hormones as ‘antiageing therapy’: the medicalization of the ageing process.

dopers in uniform.
- police officers on steroids
- brain doping by students
Chronicle of Higher Education ‘the other performance-enhancing drugs’(2004, Dec 17.)

Does a lifestyle transform a drug into a stimulant?

“I sincerely believe he didn’t see steroids as a drug, none of these kids do’

Tesosterone magazine
- if there is one, it’s probably a lifestyle, not a drug

NEJM – Aging and foundation-of-0youth hormones, paul m stewart. (Editorial)

new york times 1851

ME: treatment of syllvester stallone’s steroid episode in Australia a stunt?

ME:P If I told you that the Sylvester Stallone steroid story earlier this year was a publicity stunt to promote his film, would that change the way in which you would use it as part of your analysis?

what is medical treatment for?

‘if it gives real happiness, that is the most tha  any sufegon or medicine can giv e Dr Harold Gillies, poionieering British plastic surgeon specializing in the cosmetic repair of burned an maimed soldiers.

line between therapy and enhancement more blurred, but in sports it remains distinct.

outside of sport, enhanceemtn becoming part of acceptable lifestle goals.

Questions and Answers

Barrie: impc of context of supplement use. parallel with alcohol use – not supplement, but ubiquitous except in certain contexts, eg driving. so maintain distinction by defining context in which is seen. Also, bigger problem of maintaining definition of what a drug is – performance enhancement. athletes will not take supplements unless performance enhancing.

John: alcohol comparison important, but works one way but not another. focuses on volume of social harm that arses from use – anti-doping can make some analogies. compare social impact of steroid abuse with alcohol. but does not work in following way: putting police officer on alcohol improves performance, but if look hard enough can reconstruct dialogue of police officers on steroids – legit doping to assist in overpowering physically violent criminals. other trade ofd. chief of police of Miami said: we really should think about whether approp to put police on steroids. he was not saying it was wrong, but should think about it. now is v politically incorrect thing to say. but he identified a real dilemma. more common as something like modafinil becomes acceptable as a productivity stimulant. how are our feelings and values going to deal with this? popular wisdom in us that caffeine runs some industries.

Rob Beamish: enhancement as part of popular culture; postmodernist remaking of self; now, we remake self as part of regular way of lif. but also saw enhancement as violation of ethics. but in high performance sport, not anone who says high performance sport is a character building practice. so, enhancement not violation of ethics, but only certain types. where decide that enhancement is no longer ethical. at what point will we see steroids as non-ethical?

John: in 1990,k WHO said in Lancet that small doses of anabolic steroid were safe. research still being churned out in endocriminology. one part of the dilemma is that still in process of deciding how dangerous the drugs are. we know what anti-doping says. but, these are not the only opinions of relative risks. this remains undecided.

14.00 – 14.30
Prof. Bengt Kayser – Current anti-doping policy: harm induction or harm reduction?

doping-like behaviour

Randall, Zimmerman And Crook
prohibited from Olympic strat

kikkan randall – also natural epo peak

spirit of sport – mal defined concept

ME: deliberately so, like many ethical concepts.

repression vs potential gain

consequences of being caught
- exclusion for life

consequences of a medal
- fame and money for life

difficult to punish much more

does anti-doping work in the sense of their being less doping?
- not clear.

transport of doping drugs easier than cocaine, etc

2006 Blood, false-positive detection of recombinant human ep in urine following strenuous physical exercise
- criticised by different groups.

ME: Should WADA institute policies to protect vulnerable perspectives on anti-doping?

mike: people who disagree with your prognosis will agree with our diagnosis. disagree with ethical analysis, but agree with analysis.

14.30 – 15.00
Coffee break
15.00 – 15.30
Privat-Dozent Dr. Giselher Spitzer – Body and mind – biographical and health studies about doping victims in East German elite sport

15 years shift – what you see in doping procedures today was ‘state of the art’ before 1989

when did it start with steroids?
- blue pill oral-turinabol was 14-15yrs median
- half of sample doped before, first estimated 10 yeraas up to 14

why taking bills?
- no true answer
- others: vitamins, help traiing,  therapy

important damage and disease in sample
-    negative developments
-    damae of skeleton and muscle make normal jobs impossible (eg. longer standing, sitting, holding things). typical decision to find work was to find freelance.
-    no control group, so used brothers and sisters and offspring of each. most of the conditions are not present in these relations.

change of genotype – genetic damage
-    virilisation of foets or mandartory abortion because of pregnancy while training or a half year after competition
-    premature death while pregnancy or death birth (6 of 46 died from premature death); 3 parents have death birth
-    risk of premature death of children of doped athletes 32 times higher than normal popn; risk of death birth 10 times
-    important when considering that athletes were strong and medically well controlled
-    even control group did not have these figures

side effects on children born to athlete sing drugs
-    most of 69 surviving children also damaged
-    children of mothers who ere drugged, typically handicapped
o    37 children 54% suffer from 2 illneses
o    17 ids multiple damage
-    Dsisease represented more than 2 times:
o    every fourth child has allerges
o    one of 4 has skin illness
o    one of 4 asthmatic
o    one of 10 crippled
o    nearly one of ten metaboligc
o    1 of 7 psychic
o    1 of 17 mental disability

change of phenotype

1.    side effects: skin
a.    skin disease 12%
b.    allergies 12%

Liver
-    disease 17%

organsof body
-    damage to skeleton 92%
-    operations 67%
-    knee shoulder ankle joint 22%

25% of doped athletes have cancer or had cancer
35% sudden inflammations
17% migraine
15% metabolic
stomach 15%
epilepsy 10%
kidney 6%

disturbance of psyche and behav
-    attempts to suicide  38%
-    psychic illness 62%
-    health nutrition 25%
-    social drug
-    addiction to alcohol 13%
-    addiction to drugs 6%

side effects on male
-    testicle-atrophy or loss ability to produce sperm, 4 athletes
-    operation of testicles 3 athletes
-    enlarged prostate and treament 1 athlete
-    gynacomeastia 3 athletes (11%) (pre-cancer)
-    8 andrological diseases (29%)
o    more often than was thought

side effects on women
-    virilisation in general (breast reduction, facial hair, lowering of voice) 42%
-    injectins after maenorrhoea 4 women
-    hypertrophy of clitoris (not asked!) 0 in literature biggest size is 12cm
-    atrophy of uterus and underveloped 2 women
-    changes to ovaries – 3 women
-    generally
o    12 women gynaecological disease (50%)
o    probs with sexualidentification and identity, resulting from virilisation

no case of transexualism

7 secondary side effects as a result of higher dosese (‘overload)
- new type of damage of connecting tissue
- 7 athletes took drugs against feeling of being hungry or pills to lose water
- german masters or Olympic medallists or candidates were anxious because some gram of body mass. they stopped after reaching goal

The Value of the Results
- what we learn
first: give help to victims of mandatory oping as a humanistic need
second: knowledge to prevent re-emergence of simlar systems based on drugs eg china
third: enhancement of future policy

ME: Why do we have no good answers about what is happening in China?

other values
- value of health motor for anti doping
- boy capital is concrete guide for athletes who have to decide if they want to dope
- beyond ethical arguments, must protect own health.

Caston Lundby – rHuEPO treatment in humans: new findings and considerations for anti-doping work in the future

function of rHuEPO on blood

red cell mass ncerase, decrease plasma – total amount remains similliar

function of rHuEPO on performance

invasive studies – 6 catheters

new: epo also works at altitude. if take epo and ex at altitude, have use until 4100m approx.

so epo works for max ex intensively, but since most comps not held at max capacity, wanted to know at more suitable ex level. – how long could cycle of 80% of max to exhaustion
-    VO2max inc, but sub maximal intensities, much greater effect of epo doping.
-    not that using epo will lead to 54% increase, but that, in cycling, if break away from pack, could go for same velocity for 54% more time.

does epo have other functions than increasing oxygen content?
-    we’ve found receptor for epo in skeletal muscle (Lundby et al, AJP.
-    we’ve found no other physiological function with our model.
-    if develop more capabilities, could inc ex capacities.

to determine whether other effects,  gave subjects epo.
-    cycling exercise.
o    removed new blood from epo inducaed athletes. result showed presccie correspondence with pre-induced performance
•    suggests that effects of epo on performance related to arterial oxygen content

conclusion 1
-    rHuEPO increase arterial oxygen content by inc red cel mass decaeasing plasma vol
-    if arterial o2 inc aerobic also increase
-    m

is it dangeros to take rHuEPO.

transgenic mouse – tg6 mouse – born with 80 hematocrit. lives for 12 moths. wild type lives 24 months.
-    dies ofmulti-organ failure.

Mean Arterial Blood Pressure -0 in our substances, increased by 5-6ml of mercury – if you have this throughout your life, it is of course hazardous, but if increase to 50 and inc mercury for a few months per year for a cycling career, my guess is that it’s not so bad.

also investigated heart itself. found no dangers.

detection strategies and other

are the detection methods good?
-    abolish hematocrit level? because easily manipulated (plasma expanded, or blame sauna)
-    so, think about quantifying total haemoglobin mass, since this is constant measure usually

Hb increases with altitude exposure
Hb increases with training
Daily variation in htc
daily variation in plasma epo

so, to know whether is stable, measured in subjects – breath carbon monoxide

not clear that rapid increases in htc is blood doping

wide variation

so, this method is worthless

the on/off model

future (now) ?

epo receptor activating peptides (ERAPs)
-    do job of epo, but are not epo

when not neede, broken down immediately by
-    prolyl hydroxylase inhibitors

group in oxford has made inhibitors (DETECT FOR INHIBITOR?)

Machines to use?
-    Radiometer OSM3

Conclusion 2
-    difficult ot get htc or hb mass measure
-    machines don’t always tell the truth
-    future (and this is now…) is scary with regard to detecting endogenous epo enhancing agents

15.30 – 17.00
INHDR network meeting

19.00
Dinner in Aarhus
4
International Network of Humanistic Doping Research
www.doping.au.dk
16 August 2007
8.45 – 9.15
Coffee
9.15 – 9.45
Asst. Prof. Rob Beamish – The Policy Implications of the Current Social Construction of Steroids as a “Moral Panic”

I try to never use the word doping, since implicit illegality

Umah Bartov ‘Distorted Mirrors’
- perceptions are fundamentally important
- holocaust portrayed through series of mirrors

march 17, 2005 – committee on government reform

social constructionism
- moral panics
- claims makers
- build moral consensus

eg. house committee is one process of claims making

coubertin’s objectives have become the IOC brand

1972 munich – separate GDR
- east german successes embarrassment to west

Wade 1972 raises concern about steroids

‘the first of male steroids to improve performance is said to have been in world war II when….

1988 – 48 strides under 9.8 seconds

Trevor Graham turns in syringe with THG to USADA
BALCO
2004 State of the Union

San Francisco chronicle links Greg Anderson to BALCO who is linked to

bigorexia – young men trying to bulk up. – associated with Viagra, and other enhancements – ‘cult of the body’ within a context where drug/supplement use is widespread.

comic book masculinity

use of steroids part of postmodern world of changing faces.

Questions and Answers

John H: how long did victor conte serve in prison for balco – 3 months. grotesque disproportion of moral panic vs judicial system.

Rob: game of shadows – clear that there are thousands of BALCOs throughout America.

Paul D: mythmaking vs actual fact? how distinguish?

9.45 – 10.15
Dag Vidar Hanstad (Norwegian School of Sport Sciences) – Where on Earth was Michael Rasmussen? Elite Level Athletes and their Whereabouts
dag.vidar.hanstad@nih.no

www.sportsanalyse.com

aim
-    survey of athletes attitudes on doping
-    292 subjects, 80 responses (or was it 80?)

findings
-    80% said they trusted the online system
-    1 out of 4 felt it reduces the joy of being an elite athlete
-    signif percentage felt that 3 warnings in 18months should lead to sanction
-    many athletes felt part of a ‘big brother’ system?
-    few felt that info collected would be misused.

does tracking whereabouts violate self-determination?
need to regulate can get out of control

everyday surveillance is extensive

10.15 – 10.45
Asst. Prof. Andy Miah – Human Enhancement Technologies and Sport: The New Language of Doping?
10.45 – 11.00
Coffee break
11.00 – 11.30
Prof. Mike McNamee – Ethical issues regarding human enhancement technologies: Therapy, Enhancement and the traditional goals of medicine in sport

against doping
- performance enhancement
- allows more training – coercion
- unnatural
- harmful
- unfair advantage
- cheating

idea of enhancement
- valorization of autonomy
- are athletes generally autonomous. if not, cannot make autonomous choices
- athletes are not autonomous, do not understand sports medicine, are passive.

ME: their reliance on expert knowledge is no different from your own knowledge of medicine.

medicine is essentially therapeutic

ME: but a wide range of therapies are context driven. imagine a 70 year old man who can no longer enjoy a sex life. is the prescription of Viagra therapy or enhancement? Alternatively, an individual who has a known late onset genetic condition for which there is an ongoing treatment – you are likely to get Parkinson’s, we should start treating you now’ your characterisaton of these as peripheral to your concerns is mistaken. they are the business of all medicine.

doesn’t follow that what happens within a hospital is all therapy

night and day, cannot tell you when one begins. – ME: yes you can mike, it’s when you wake up

‘there will be cases which are not therapy/enhancement, I don’t have a problem with that’
- ME: that’s precisely the problem you have

demarcate unacceptable enhancement
use of prosthetics in elite disability sport

how desirable is the fact that the performance is dependent on technology? (Loland)
prob is surrending level of control athlete has over daily life
-    ME: so, an athlete that wants to stay at home with family, cannot afford to take them to mountain, her quality of life is diminished by not using hypobaric

will what is left be recognisably human?

Questions for Mike:
1.    if your claim is that athletes are passive – ie. not autonomous – then I also doubt my own understanding of . there is no legal basis for supporting the claim that athletes lack autonomy. In 1985, the case of Gillick vs West Norfolk established what’s called ‘Gillick Competence’. it indicated conditions where minors could obtain abortion without requiring parental consent. it has become a critical part of how we think legally about autonomy and consent. there is no way imaginable that you could argue legally that athletes are not autonomous to such an extent that you could step in for them to decide on the basis of some ‘substituted judgement’. Over the last year, my doctor has quadrupled my preventative prescription for asthma. I’m not sure I understand the medical science too well. I feel like I might be building an unhealthy resistance, but there is no doubt that I have autonomously acceded to this treatment.
2.    Medicine makes us well ‘for something’ it is never free from the lifestyles we want to lead.

11.30 – 12.00

Director Michele Verroken – Anabolic Steroid Use – what is the size of the problem for sport and society?

reliability of data = credibility of information

test date from 1993-2003

no of samples increased from 89166 to 151210

no of anabolic steroid findings inc from 940 to 1169 (872+297 – includes beta 2 agonists)

question – is an approx 2% problem, a problem?

in 2002-3, Australia reported only .59% positive test.

we don’t know about the problem

survey of athletes 1998

54% believe that up to 30% of competitors in their sport were using performance enhancing drugs

4% said 60% were doing so

3% (none from weightlifting or rugby league) believed sport was clean

(from the Indenendent)

new york times 2003
‘how many athletes in us use steroids’
results do not reflect testing data?

also asked whether it bothered people – 30-40% said no.

realibility of testing, random, missed test scenarios

many athletes say random testing is actually targeted.

positive test over the years not significant percentage.

ME: ou mention Beijing. what do we know?

are we helping ourselves by identifying the size of the problem.

better to miss a test than fail a test.

more than 70 British athletes have missed at least one out of competition drug test. 4 of them have missed 2.

IAAF regs say a missed test is for five years, not just 18 months.]

testosterone reporting

testosterone-epitestosterone ratio
- upto 2004: 6:1
- post 2004:

Autologous blood injections in soft tissues complaint

alice in wonderland
‘I don’t think they play fairly…’

£2000 to treat abscess from steroid injectors – if teach to inject properly, lower the cost.

future social problems?
- France BJSM research – 1/100 of eleven year olds use drugs to enhance performance (could be salbutamol)

we know there are inconsistencies between sport and society use of steroids

to WADA
- tighten up testing – not government targets
- promote health consequences of using steroids and opportunities of needle exchange.

12.00 – 13.00
Lunch
13.00 – 13.30
Prof. Alessandro Donati – Connections between doping and narcotic drugs

Australian anti-doping agency – image vs performance enhancing drugs

Schwarzenegger was paid by mafia directly for his films

combination of doping and training knowl
- day of athlete now is full of training – cannot do other things.
- e.g. many cannot read more than 10 books a year
- rogge now interested in youth – fight obesity and sedentary – so, youth Olympic games
- no connection between doping and obesity/sedentary.
- clear that athletes use undetectable drugs, not the others
- anti-doping tests died.
- dick pound says they’ve improved, which is true, but prob is that anyone can modify and disguise drugs.
- we need anti-doping, but not only.

source of proof
- in sport – only test
- in judicial system – searches, seizure, wire ttapping, expert reports, test biology, documents

what is hidden behind high number of negative tests?
- suffer from asthma, high testosterne or hmb
- hides anomalous levels – pathologies behind results
- interest in lives or appearance – I think only appearance
egs.
- upward trend of cholestorol levels through t years. why?
- unexplained fluctuations of haematocrit and haemoglobin levels (more than 20%)
- critical fluctuations of liver transaminase..also azotemia, bilirubin and several other parameters

negative anti-doping hides emerging disease conditions.

electronic health passport is a good idea.

why do we need state laws against doping?
-    every country should pass criminal laws against doping or update existing laws concenring addictive and pharmaceutical substances that would allow effiecient action to contrast t diffusion of doping among amateur athletes and in gymnasia.

mistake in Italian law is that specifies for elite athletes, it should be everywhere.

ME: if the law should be for everyone where else do you want to police usage? schools, gymnasia,

sport system is scarely efficient as regards acquistion of proof but decisions on sanctions are taken swiftly, but process much longer

dishonest officials stay in the environment, while athlete is out.

the old ioc was a disaster. now we hope wada, but we are late

connections between doping substances and social drugs

common ground – cocaine, stimulants, amphetamines heroin, opiates narcotics cannabis, ghb, alcohol.

sport system

difficult to accept sport system.
athlete positive for cocaine. he never went to disco. when is he going to use cocaine for social?

antidoping lasws in eujrope

legal systems on dupong
- in June 2006, Italian minister for social affairs appointed me fconsultant

doping substances are assimilated to addictive drugs so that the judicial instruments and the anti drugs criminal las…

se of doping substances not criminal offence for common practiconers but only for professional athletes….because doping gives them an illicit advantage and damages their opponents
- create indiv health smart card for all practioners of sport federation.
- not important to disqualify, but to stop
- inverstigations coordinated by special police squad
- contrast traffic of doping substance via the internet

Article 28, item 4, establishes internet acess providers….

Slovenia
- websites in several countries
-

ME:

13.30 – 14.00
Asst. Prof. Ask Vest Christiansen – The use of anabolic-androgenic steroids among non-competitive strength training athletes – cultural, social, and psychological explanations

campaigns against non-competitive strength trainers has failed, why?
portrait of a person who took a lot of steroids and loved it
presentation of types of questions received by Anti-doping denmark

1999 national household survey on drug abuse – estmate 3m users of steroids in US
ADD estimates between 10,000-60,000 in Denmark
inexactness reveals how little we know
4 of 5 steroid users are non-athletes
in Denmark: 9/10 users non-athletes
steroid users larger doses today than previously reported
widespread misconception that trainin for improving appearance can only succeed with combined drugs and training

have tried to change things by imposing fear

a paradigmatic change – not just a medical prob but a cultural phenonmenon

take into account cultural norms and values of drug inflicted subcultures

campaigns have been based on bourgeious values, v different from cultures of body-builders

focus of campaigns have focused on side effects and consequences – impotence, acne, damage to vital organs.

subjective experience of drugs vary
- inc stength, virtality, libido, social status

a Danish bodybuilder
- said how use of drugs gave 2 fantastic years of building, but ultimately spiralled out of control.
- from compettive football, but disillusioned. realised potential for muscle building. was well proportioned. but after progress, muscle development levelled off. decided to continue development with steroids. began with anabolic, to nanobolic – injecting 150-250 mg per week – more effective and no side effect of subcut fat, as pills did. achieved high recognition in his milieu. strict diet. other things mattered less. when met a girl, made clear should not complain about his use. experienced none of the side effects, never violent. but lost control of medicine. intervals between treatments completely disappeared. did not bother him at first, but became ill. 3 weeks before contest, body broke down. hospitalized. in recovery, realized seriousness, before moving depression. he felt something was taken from him. – injustice that had not been able to finish project. now recovered and teaching in small village school.
- what can be learned?
- male status of muscles is crucial to understanding doping of weight training
- promise of transformation.

Alan Klein ‘little big men’ – promise of change, from vulnerable to heroic and opposing.

14.00 – 14.30
Coffee
14.30 – 15.00

Prof. Verner Møller – Is the current anti-doping strategy satisfactory, and can it be improved?

doping is what wada assesses it to be

prob not that you dope, but how you dope

eg. caffeine – taken off list, despite being a stimulant
why not oppose vanity dopng?

tamburrini – what is wrong with doping?

fact that doping rules are arbitrary does not mean they are mistaken.
second claim by tamburrini, is that open access would be discovery of actual risks.
-    other areas suggest restrictive use leads to

in spite of these reasons, threre is support for anti-doping

so what is wrong with doping? nothing if ultra-liberalistic perspective

Questions and Answers

Claudio: is the reason for so few doping injuries evidence of underground doping research?

15.00 – 15.30
Final discussions
15.30 – 16.00
Epilogue
17.15
Visit and buffet at City Hall

Theory, Culture, Society (2007, Tokyo)

TCS Japan
14 july 2007

Bernard Stieglar
medical science
therapy
care for the body – gymnastics
becoming
technics
husserl – idos – intentional core of all phenomena
question of telos – in WiMAX and ubiquitous technology – to be at a distance and everwhere
question of knowing what being
ontoteleology as milieu of ontogenesis
collectuve desure as therapy
death of philosophy in era of wimax
psychical/technical/symbolic associated milieu

symbolic
-    associated since connects at a distance, while recognising, constituted by milieu

virtual
potential
find myself objectified
encounter the other through another
long circuit – otherness – singularity mirrored by – ego other
desire – gift and countergift inscribes loop
object of desire received only as much as open
co-operative technologies
recipients also senders

steven scweig – chess player

Barbara maria stoppard

long conscious look
argument to connect certain aspect of contemporary neuroscience and what has happened in culture with regard to diminishment of conscious attention
Philip toledano – photos of people watching computer games
theoretical perspective
rise of extended interest in systems self-assembly –
self-assembly in Aristotle
earl modern component – organisation of matter – auto org – external has no control
palengenesis
French late 18th C
organic fascination with self-replication
crystallography
systems of self assembly
installation art theme
andy Goldsworthy – like science counterparts interested in process of self generation
roger penrose
dynamics of living cell
medical community – fibrillations of art
all are autosystems
nanotechnology
particulary interesting, since indicates exponential increase of interest in systems that are autopoietic at deepest level
nano or genetic systems not only novel, but that they impart precise level of control over interactions
not top-down perspective
massive interest in
brain as largely closed system
Darwinist component
different camps in neurosciences
massive research focus on autopoietic focuses
mental neural systems are not simply closed

3 points
vanishing of selective attention
emerge from modern neurobiology
important for visual education – sensory based
reversals of powerful earlier epistemological models
1.    cognition does not function like seeing (from Plato to Locke – demise of picture theory model of mind; limited definition of image in neuroscience; ironic since microstudy of vision has continued)
2.    one of chief waves of neuroscientists bridge humanities and scientists – adopting social issues to medical – harnessing of desire – functioning of inferencing – how much that brings to world that is part of intimate neural structure.)
3.    neurosciences have dilated perception. perceptual acts are part of entire sensorium. recognition that motion and vision are indisolvable. motion is primary. kinesis is central to all aesthetic knowing. predecssors in art – 1960s expt art – bridget riley, who realized conception of an expanded eye. victor basoreli – connections between the two – proleptic of some realizations of today – ability of putting primacy of motor experience with vision – performatively and phenomenologially dissolve gap between subject and object – back to plato – this fact suggests must consider pedagogically of instantiating situationist studis rather than film or media studies – consider estab of new study programme not dominated by continuous strip models of film, video and other projection – eg. in words of dewey or james – that is relational – relating physio and psyche to event – we already have a model – in installation work that is phenomenologically inflected – not ponty – cognitively cognizient – uliver alieson – eye integrated with multicipicty of appearances – immersive – deep anthropothentrized -  embedded within situation – intersection of event and subject

if consider VR CAVEs, political isolationism, home schooling
hardly surprising that closed autopoiesis will become major ruling … for better or worse
paradigm of efficient – automated info transfer

if science goes into understanding inner
what about public forms of communication?
if human brain models world for indiv, why confront al to test potential?

workspace model – hypothesise in relationship to other info – question: why go outside in search of context – la verite – why? given massive internal apparatus
why not just linger among unconstrained alternatives

need a new kind of education – situationism, which takes into account pre-attentive scheme and how become ampligied by selective attention

counter intuitive argument:  against romantics that creativity lie in escaping, not giving into autopoietic machinery and focusing on world – such against the grain externally focused attentiveness or, working on the world is made even more difficult by proliferation of mobile media – technologies of the blink – made to be intrinsically compatible with brain’s endlessly remot control – iphone for eg – range from solipsistic system and filtering devices – bose headphones – Damien hirst – taylorization of medicine – painting made out of valium – tailored medicine – zooms in on those systems that are beyond our control – in control of someone – else – Wittgenstein: seeing not seeing as enables knowledge to grow.

commentaries

steiglar on Stoppard
taking care of care,
chapter on paying attention
attention for me is central theme in my endeavours

heteronymy
dependence on other things
using freud – within heteronymy – how to dissociate issue
in formation of attention, form of support, when you talk I listen, when you talk I listen – in accordance with autopoiesis

organology – in French – word for tongue and language is the same – tf in a certain environment, tongue becomes a language.

lunch

1300

biopolitics

john marks, French dept, uni of Nottingham
posthuman and inhuman
3 authors: Dominique janicoaux, henri atler – la science et inhuman?, Eugene thacker – biomedia
speculation of posthuman future
range of technological treatments – genetic screening, therapeutic cloning, reproductive cloning, mind uploading, nanotechnology
future where we might cease to be human
become superhuman – extropian posthumanists
cyborg humanity – immortal – silicon support for human brain
potentially acknowledged by janicoax – ‘will man go beyond the human’ – robust human race – extremely quick and heightened sensory
common reaction to posthuman has been to defend integrity of human
habermas – human freedom depends on ethical imperative of reating as end of him/her self – arendt’s concept of natality
fukuyama – fears human nature which underpins economic competitive system – undermined by future biotechnological dvances – ME, BUT ACTUALLY THE COMMERCIAL CHARACER OF THEM –
others havequestioned
much talk about posthuman seems to neglect criticism of humanism – janicoax mentions heidegger’s humanism as response to existentialism
janicoax – relationship of man to being – learn to go out from himself
janicoax – drawing on pascaule – human condition is one of division between inhuman and superman – persistant inhumanity of human kind reminds of abyss of inhuma, constantly threatening to undermine humanist aspirations – utopian notion of overcoming, fraught with dangers of inhumanity. but should remain open to what surpasses man in man. overcoming of limits that are part of our humanity.
but janicoax is elusive – relies on assertion of what is core set of human atrtributes ‘ on the essentials..conscious, free, finite, choosing between good and evil…nothing has changed’
could reply, no, but it might
fails to engage fully with potential difference of future human conditions
he remarks that ‘myth of the cyborg’ says more about current fears, rather than any posthuman
also prob of extropian
thacker: this view consciously models itself on conventional humanism – enhanced human qualities
missing a thorough engagement with technological inhuman – eg educationali opening up of human
only see glimpses in janicoax

thacker: modify contemporary bioethics kantian foundation

conventional bioethics thinks of body in straighfotward – how a body can be good

ME – WHICH CONVENTIONAL BIOETHICS?

thacker proposes bioethics

new: Spinoza’s bioethics – particles standing in relationship to each other
bioethics asks, what is a body, what can it do and what can be done to it

ME – I THINK YOU ARE DISCUSSING MEDICAL ETHICS or INSTITUTIONAL ETHICS, RATHER THAN BIOETHICS.

atlan – cloning, embryo – misunderstanding – cellular unit resulting from process of cloning, does not exist in nature. can development into embryonic stem cells, rather than define as embryo, think of as an evolving process, rephrase ethical question – something that is not an embryo may become a human being and something that is not a human maybeco….. artifact from reprod cloning is an inhuman body –

Questions and Answers

HENRI ATLAN – WAS ON THE FRENCH BIOETHIC ADVISORY COMMITTEE

question: death makes us human, end of death – posthuman; retaining possiblility of death –

tammy lynn castellian
Heidegger and world war 1

effect of implementation of gas in world war I, first instance of biopolitical regime

MONDY 5PM

hassal?
the diachronic thing
from book on media and time

1.    there is no time in itself, only time as measured (Aristotle)
2.    because movement is a techincal operation, time is technical
3.    because time is technical, be measured by non-human being

extrasubjective

role of media is to measure time.
chronos – Dominique janicroux – authentic from inauthentic time
experienced or lived from technical time
time never pure, always measured
clock time not homogenous unity
relatively under constantly control
two senses of measure – no strict divide between measured and experienced
technics is condition of primary presencing
cinema operates by capturing the time of consciousness
alternate possiblitis to live timee wll not follow automatically from presence of these devices in our world
came from military industrial complex
struggle over presencing
non-reducability of time
digital technology exposes a reality of time that is more difficult but not impossible to tap
artist: Pierre quieeg
politics of presencing
time cannot exist without mediation, nor any particular

KAT
spimes – space plus time – bruce sterling
-    track objects in time and space, never before possible
different from ubc since this identifies  a specifc tag

the control society
US requiring countries with visa waiving to have rfid chips
-    will soon include biometric data within chip

deleuze – postscript on a control society
-    from disciplinary society (confinemet and control of bodies) to control society (flows of info)

anti-rfid activism
Spychips – book – Katherine Albrecht – liz mcintyre

Philip k dick – ubik –

a crisis of interpretation
ed fradkin ‘digital philosophy’ – believes universe is fundamentally computational
‘the meaning of information is given by the process that interprets it’

mp3 player – gives meaning to a file by producing audio waves

restore contexuality

Shannon did not see how he could do

also, multiple layers at which info is given meaning – from binary to C++

processual view of information by taking what meaning and interpretation connote

now meaning and interpretation not only functions of higher capacities, but can be performed in v humble ways by mp3 and human understanding

all of these dynamic hierarchies are recursively related to one another

implications for subjectivitiy

‘what is changing is not merely the terminology or metaphorical representation of subjects, but the very structreu of subjectivity, social relations and t social imaginary that supports it’ braidotti metamorphses

hayles@humnet.ucla.edu